ArticleJournal of the American Chemical Society2016
Ligand-Promoted meta-C-H Amination and Alkynylation.
Article in Journal of the American Chemical Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed.
- A Generalized Approach for Distal C-H Arylation of Organic Building Blocks: Unveiling the Role of Counter Anion.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Metal and Additive-Free Nondirected Meta-C-S Bond Formation on Anilines: Toward Biologically RelevantACS central science · 2025Article
- Article
- Advances in Vicinal Dicarbo-C-H-functionalization of Five-Membered Heteroarenes via Palladium/Norbornene Cooperative Catalysis.Tetrahedron letters · 2025Article
- Metal-free para-selective C-H amination and azidation of N-arylhydroxylamines.Nature communications · 2025Article
- Diversity-Oriented C-H Activation Reactions of the Naphthalene Scaffold.Journal of the American Chemical Society · 2025Article
- From Mono-Accounts of chemical research · 2025Review
- Meta-Dimethylation of Arenes via Catellani Reaction from Aryl Thianthrenium Salts.Angewandte Chemie (International ed. in English) · 2025Article
- Palladium (II)-Catalyzed C-H Activation with Bifunctional Ligands: From Curiosity to Industrialization.Angewandte Chemie (International ed. in English) · 2024Review
- Directing group assistedChemical science · 2023Article
- S,O-Ligand Promoted meta-C-H Arylation of Anisole Derivatives via Palladium/Norbornene Catalysis.Angewandte Chemie (International ed. in English) · 2022Article
- Pd(ii)-catalyzedChemical science · 2022Article
- Directing group assisted rhodium catalyzedChemical science · 2022Article
- Site-selective amination and/or nitrilationChemical science · 2022Article
- Selective Para-C-H Alkynylation of Aniline Derivatives by Pd/S,O-Ligand Catalysis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Structurally Modified Norbornenes: A Key Factor to Modulate Reaction Selectivity in the Palladium/Norbornene Cooperative Catalysis.Journal of the American Chemical Society · 2020Review
- Facilitating Ir-Catalyzed C-H Alkynylation with Electrochemistry: Anodic Oxidation-Induced Reductive Elimination.ACS catalysis · 2020Article
- meta-Selective C-H Arylation of Fluoroarenes and Simple Arenes.Angewandte Chemie (International ed. in English) · 2020Article
- Dibenzothiophenesulfilimines: A Convenient Approach to Intermolecular Rhodium-Catalysed C-H Amidation.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020Article
- Ligand-Enabled Pd(II)-Catalyzed C(spOrganic letters · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Using a modified norbornene (methyl bicyclo[2.2.1]hept-2-ene-2-carboxylate) as a transient mediator, meta-C-H amination and meta-C-H alkynylation of aniline and phenol substrates have been developed for the first time. Both the identification of a monoprotected 3-amino-2-hydroxypyridine/pyridone-type ligand and the use of a modified norbornene as a mediator are crucial for the realization of these two unprecedented meta-C-H transformations. A variety of substrates are compatible with both meta-C-H amination and meta-C-H alkynylation. Amination and alkynylation of heterocyclic substrates including indole, indoline, and indazole afford the desired products in moderate to high yields.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.