ArticlePediatric transplantation2016
Post-transplant blood transfusions and pediatric renal allograft outcomes.
Article in Pediatric transplantation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- Challenges in perioperative blood transfusions in kidney transplantation and the need for Patient Blood Management.Blood transfusion = Trasfusione del sangue · 2024Observational
- Anemia after kidney transplantation.Pediatric nephrology (Berlin, Germany) · 2023Article
- Clinical impact of early post-transplant red cell transfusions in kidney transplantation: a systematic review and meta-analysis.Frontiers in transplantation · 2023Review
- Acute kidney injury secondary to urinary tract infection in kidney transplant recipients.Scientific reports · 2022Article
- Anemia in Pediatric Kidney Transplant Recipients-Etiologies and Management.Frontiers in pediatrics · 2022Review
- Post-Transplantation Early Blood Transfusion and Kidney Allograft Outcomes: A Single-Center Observational Study.Transplant international : official journal of the European Society for Organ Transplantation · 2022Observational
- Early Post-Transplant Red Blood Cell Transfusion Is Associated With an Increased Risk of Transplant Failure: A Nationwide French Study.Frontiers in immunology · 2022Article
- Early Posttransplant Blood Transfusion and Risk for Worse Graft Outcomes.Kidney international reports · 2021Article
- Blood Transfusion and Adverse Graft-related Events in Kidney Transplant Patients.Kidney international reports · 2021Article
- Immunological Risk Factors in Paediatric Kidney Transplantation.Research and reports in urology · 2021Article
- Anaemia requiring red blood cell transfusion is associated with unfavourable 90-day survival in surgical patients with sepsis.BMC research notes · 2018Observational
- Prevalence and predictors of blood transfusion after pediatric kidney transplantation.Pediatric nephrology (Berlin, Germany) · 2018Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
The association of blood transfusions with GS after pediatric KTx is unclear. We retrospectively analyzed blood transfusions post-KTx and subsequent outcomes. Between 1984 and 2013, 482 children (<18 years of age) underwent KTx at our center. Recipient demographics, outcomes and transfusion data were collected. Cox regression with post-KTx blood transfusion as a time-dependent covariate was performed to model the impact of blood transfusion on outcomes. Of the 208 (44%) that were transfused, 39% had transfusion <1 month post-KTx; 48% >12 months. Transfused and non-transfused recipients were not significantly different. In univariate and multivariate analyses, there was no difference between transfused and non-transfused recipient patient survival, antibody-mediated and ACR, and DSA free survival. Transfusions <1 month post-KTx did not impact DCGS (P=NS). Patients transfused >12 months post-KTx had significantly lower 12 month eGFR (compared to non-transfused) and worse subsequent DCGS. Post-KTx blood transfusions have increased in pediatric KTx over time but have no negative association with rejection or DSA production. DCGS is unaffected by transfusion within first month. Transfusions after the first year occur in patients with more advanced chronic kidney disease and are associated with significantly worse DCGS.
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Registered trials
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