ReviewPLoS neglected tropical diseases2016
Zoonoses As Ecological Entities: A Case Review of Plague.
Review in PLoS neglected tropical diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
- Effects of fipronil bait pellets on two cricetid species: Potential implications for plague mitigation and wildlife conservation.International journal for parasitology. Parasites and wildlife · 2026Article
- Development of a Multiplex TaqMan Real-Time PCR Assay for the Simultaneous Detection and Differentiation of Three PathogenicVeterinary sciences · 2026Article
- Identification of Ctenocephalides felis felis and the detection and characterization of associated Wolbachia endosymbiont in Pakistan.BMC veterinary research · 2026Article
- Virulence Reduction inBiomolecules · 2025Article
- First assessment of plague in terrestrial small mammals and fleas from Makira Natural Park and surroundings, North-eastern Madagascar.PLoS neglected tropical diseases · 2025Article
- Plagued by the Past, Pressed by the Present: A One Health Perspective onBiomedicines · 2025Review
- Prairie dog responses to vector control and vaccination during an initialInternational journal for parasitology. Parasites and wildlife · 2024Article
- Wildlife as Food and Medicine in Brazil: A Neglected Zoonotic Risk?Pathogens (Basel, Switzerland) · 2024Review
- Species-level microbiota of ticks and fleas fromFrontiers in microbiology · 2023Article
- Analysis of complete mitogenomes and phylogenetic relationships ofFrontiers in veterinary science · 2023Article
- A Role for Early-Phase Transmission in the Enzootic Maintenance of Plague.PLoS pathogens · 2022Article
- Exploring and Mitigating Plague for One Health Purposes.Current tropical medicine reports · 2022Article
- Spatiotemporal analysis of bubonic plague in Pernambuco, northeast of Brazil: Case study in the municipality of Exu.PloS one · 2021Article
- HIV transmission and source-sink dynamics in sub-Saharan Africa.The lancet. HIV · 2020Review
- Plague in Zimbabwe from 1974 to 2018: A review article.PLoS neglected tropical diseases · 2019Review
- Living with plague: Lessons from the Soviet Union's antiplague system.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Disease reservoirs: from conceptual frameworks to applicable criteria.Emerging microbes & infections · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As a zoonosis, Plague is also an ecological entity, a complex system of ecological interactions between the pathogen, the hosts, and the spatiotemporal variations of its ecosystems. Five reservoir system models have been proposed: (i) assemblages of small mammals with different levels of susceptibility and roles in the maintenance and amplification of the cycle; (ii) species-specific chronic infection models; (ii) flea vectors as the true reservoirs; (iii) Telluric Plague, and (iv) a metapopulation arrangement for species with a discrete spatial organization, following a source-sink dynamic of extinction and recolonization with naïve potential hosts. The diversity of the community that harbors the reservoir system affects the transmission cycle by predation, competition, and dilution effect. Plague has notable environmental constraints, depending on altitude (500+ meters), warm and dry climates, and conditions for high productivity events for expansion of the transmission cycle. Human impacts are altering Plague dynamics by altering landscape and the faunal composition of the foci and adjacent areas, usually increasing the presence and number of human cases and outbreaks. Climatic change is also affecting the range of its occurrence. In the current transitional state of zoonosis as a whole, Plague is at risk of becoming a public health problem in poor countries where ecosystem erosion, anthropic invasion of new areas, and climate change increase the contact of the population with reservoir systems, giving new urgency for ecologic research that further details its maintenance in the wild, the spillover events, and how it links to human cases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.