ArticleJournal of perinatology : official journal of the California Perinatal Association2017
The effects of human milk fortification on nutrients and milk properties.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Nutritional Composition and Energy Content of Donor Human Milk: A Systematic Review.Advances in nutrition (Bethesda, Md.) · 2020Pooled it
- Osmolality of fortified human milk with contemporary human milk fortifiers.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026Article
- Point-of-care human milk concentration by passive osmosis: comprehensive analysis of fresh human milk samples.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Effect of fortification on the osmolality of human milk.Italian journal of pediatrics · 2023Article
- Human milk pH is associated with fortification, postpartum day, and maternal dietary intake in preterm mother-infant dyads.Journal of perinatology : official journal of the California Perinatal Association · 2023Observational
- Fortification With Bovine Colostrum Enhances Antibacterial Activity of Human Milk.JPEN. Journal of parenteral and enteral nutrition · 2021Article
- Do Maternal Factors and Milk Expression Patterns Affect the Composition of Donor Human Milk?Nutrients · 2021Observational
- Early Enteral Feeding in Preterm Infants: A Narrative Review of the Nutritional, Metabolic, and Developmental Benefits.Nutrients · 2021Review
- Olfactory Cues in Infant Feeds: Volatile Profiles of Different Milks Fed to Preterm Infants.Frontiers in nutrition · 2020Article
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Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the effects of fortification and storage on nutrients and properties of various human milk (HM) types. STUDY
designMother's own milk (MOM) and pasteurized donor human milk (DHM; n=118) were analyzed pre- and post fortification with Enfamil and Similac human milk fortifier (EHMF and SHMF) before and after 24 h of refrigerated storage.
resultsMilk fortified with SHMF had significantly greater osmolality, pH and lipase activity than EHMF. Changes in protein, pH and osmolality following refrigerated storage differed between fortifiers. When milk type was factored into the analysis, protein and lipase activity changes in fresh MOM differed significantly from DHM and frozen MOM. Analysis of UNF HM found higher protein levels in preterm vs term samples and in MOM vs DHM.
conclusionNutrient composition of HM varies significantly by milk type. Although fortifiers enhance select nutrients, each has the potential to affect HM properties in a unique way and these affects may vary by milk type.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.