Evidence map›Paper›PMID 27710011›Full record

ArticleAmerican journal of respiratory and critical care medicine2017

Cystic Fibrosis: The Dawn of a New Therapeutic Era.

Sonya L Heltshe, Jonathan Cogen, Kathleen J Ramos, Christopher H Goss

Abstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sonya L Heltshe1 Division of Pediatric Pulmonology, Department of Pediatrics, and.
Jonathan Cogen1 Division of Pediatric Pulmonology, Department of Pediatrics, and.
Kathleen J Ramos3 Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington, Seattle, Washington; and.
Christopher H Goss1 Division of Pediatric Pulmonology, Department of Pediatrics, and.

Funding

Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI Sonya Heltshe · 2010 to 2026
$21.4M
Proof of Principle Evaluation of IV Gallium Nitrate in Patients with CFUM1HL119073 · NHLBI · UNIVERSITY OF WASHINGTON · PI GOSS, CHRISTOPHER HOOPER, SINGH, PRADEEP K · 2013 to 2017
$4.8M
Early Intervention in Pulmonary Exacerbation in CFR01HL103965 · NHLBI · UNIVERSITY OF WASHINGTON · PI GOSS, CHRISTOPHER HOOPER, LECHTZIN, NOAH · 2010 to 2014
$3.8M
The relationship of fecal microbiomes and nutritional status in CFR01DK095869 · NIDDK · UNIVERSITY OF WASHINGTON · PI HOFFMAN, LUCAS R, MILLER, SAMUEL I · 2014 to 2018
$3.2M
Investigating treatment resistance mechanisms in chronic bacterial infectionsR01AI101307 · NIAID · UNIVERSITY OF WASHINGTON · PI BRUCE, JAMES EDWARD, MANOIL, COLIN · 2012 to 2016
$2.9M
A prospective trial of oral azithromycin when added to inhaled tobramycin in CFR01HL124053 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI NICHOLS, DAVID PAUL · 2015 to 2019
$2.8M
Regulation of host inflammatory responses and outcome in melioidosis by TLR5R01HL113382 · NHLBI · UNIVERSITY OF WASHINGTON · PI WEST, TIMOTHY EOIN · 2012 to 2016
$2.6M
Phase 2 Study of Intravenous Gallium Nitrate in the Treatment of Cystic FibrosisR01FD003704 · FDA · UNIVERSITY OF WASHINGTON · PI GOSS, CHRISTOPHER HOOPER · 2009 to 2018
$2.0M
Baby Observational and Nutritional Study of Cystic FibrosisR01DK095738 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI BOROWITZ, DRUCY, RAMSEY, BONNIE W · 2012 to 2015
$1.6M
Lung Transplant Referral for Cystic Fibrosis Patients with Advanced Lung DiseaseF32HL131246 · NHLBI · UNIVERSITY OF WASHINGTON · PI RAMOS, KATHLEEN JESSICA · 2016 to 2016
$29k
FDA HHS R01 FD003704NHLBI NIH HHS F32 HL131246NHLBI NIH HHS R01 HL103965NHLBI NIH HHS R01 HL113382NHLBI NIH HHS R01 HL124053NHLBI NIH HHS UM1 HL119073NIAID NIH HHS R01 AI101307NIDDK NIH HHS P30 DK089507NIDDK NIH HHS R01 DK095738NIDDK NIH HHS R01 DK095869
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AminophenolsAminopyridinesBenzodioxolesChloride Channel AgonistsCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorDrug CombinationsEarly DiagnosisGenetic TherapyHumansQuinolonesSurvival RateAminophenolsAminopyridinesBenzodioxolesChloride Channel AgonistsCystic Fibrosis Transmembrane Conductance RegulatorDrug Combinationsivacaftorlumacaftor, ivacaftor drug combinationQuinolones

Identifiers

PMID27710011
PMCPMC5422649

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.