ArticleJournal of Korean medical science2016
Distribution of Diseases Causing Liver Function Test Abnormality in Children and Natural Recovery Time of the Abnormal Liver Function.
Article in Journal of Korean medical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Distinct age-dependent phenotypes of abnormal liver function tests derived from national Emergency Department data.Clinical and experimental pediatrics · 2026Article
- Acute severe hepatitis in children following extrahepatic infection in South Korea: etiology, clinical course, and outcomes.Acute and critical care · 2025Article
- A Report on a Nationwide Surveillance System for Pediatric Acute Hepatitis of Unknown Etiology in Korea.Journal of Korean medical science · 2023Article
- Kawasaki Disease with Hepatobiliary Manifestations.Medicina (Kaunas, Lithuania) · 2022Article
- [Association of liver damage with coronary artery lesion and no response to intravenous immunoglobulin in the acute stage of Kawasaki disease].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022Article
- Liver Involvement in Acute Respiratory Infections in Children and Adolescents - Results of a Non-interventional Study.Frontiers in pediatrics · 2022Article
- A Multicenter Study of Real-world Practice for Management of Abnormal Liver Function Tests in Children with Acute Infectious Diseases.Journal of Korean medical science · 2021Article
- Atypically Protracted Course of Liver Involvement in Kawasaki Disease. Case Report and Literature Review.Pediatric reports · 2021Article
- Hepatoprotective activity of okra (Veterinary world · 2020Article
- Clinical implications of aminotransferase elevation in hospitalised infants aged 8-90 days with respiratory virus detection.Influenza and other respiratory viruses · 2020Observational
- Revision of serum ALT upper limits of normal facilitates assessment of mild liver injury in obese children with non-alcoholic fatty liver disease.Journal of clinical laboratory analysis · 2020Article
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4 authors at 1 institution in 1 country.
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Abstract
Although liver function test abnormality is frequently noted in children, there is no report about the distribution of the etiology and natural recovery time of the abnormal liver function. From March 2005 to February 2014, clinical information was retrospectively collected from 559 children who had abnormal liver function and were hospitalized or visited the outpatient clinic at the Jeju National University Hospital. The etiology of abnormal liver function was classified into groups and the natural recovery time of abnormal liver function was analyzed. The etiological groups of 559 patients included 'nonspecific hepatitis' in 42 (7.5%), 'infection' in 323 (57.8%), 'rheumatologic and autoimmune' in 66 (11.8%), 'nonalcoholic fatty liver disease' in 57 (10.2%), 'anatomic' in 12 (2.1%), 'toxic' in 13 (2.1%), 'metabolic' in 8 (1.4%), 'hematologic' in 7 (1.3%), 'hemodynamic' in 4 (0.7%), and 'others' in 27 (4.8%). Among the 'infection' group (57.8%), the 'viral infection in the respiratory tract' subgroup, which had 111 patients (19.8%), was the most common. The natural recovery time of the abnormal liver function was 27 days (median) in 'nonspecific hepatitis', 13 days (median) in 'viral respiratory tract disease', 16 days (median) in 'viral gastroenteritis', 42 days (median) in 'viral febrile illness", and 7 days (median) in "Kawasaki disease". The information on the natural recovery time of abnormal liver function may help the physician to perform good clinical consultation for patients and their parents.
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