Evidence map›Paper›PMID 27709490›Full record

ArticleMolecular neurobiology2017

Atorvastatin Protects from Aβ

Fabiana K Ludka, Maurício P Cunha, Tharine Dal-Cim, Luisa Bandeira Binder, Leandra C Constantino, Caio M Massari, Wagner C Martins, Ana Lúcia S Rodrigues, Carla I Tasca

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  14. Physical exercise prevents amyloid βMetabolic brain disease · 2021
    Article
  15. Article
  16. Involvement of adenosine APurinergic signalling · 2020
    Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Fabiana K LudkaDepartamento de Bioquímica, CCB, UFSC Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, 88040-900, Brazil. fabianakalyne@hotmail.com.
Maurício P CunhaPrograma de Pós-graduação em Bioquímica, Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, 88040-900, Brazil.
Tharine Dal-CimPrograma de Pós-graduação em Bioquímica, Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, 88040-900, Brazil.
Luisa Bandeira BinderDepartamento de Bioquímica, CCB, UFSC Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, 88040-900, Brazil.
Leandra C ConstantinoPrograma de Pós-graduação em Bioquímica, Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, 88040-900, Brazil.
Caio M MassariPrograma de Pós-graduação em Bioquímica, Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, 88040-900, Brazil.
Wagner C MartinsPrograma de Pós-graduação em Neurociências, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, 88040-900, Brazil.
Ana Lúcia S RodriguesDepartamento de Bioquímica, CCB, UFSC Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, 88040-900, Brazil.
Carla I TascaDepartamento de Bioquímica, CCB, UFSC Universidade Federal de Santa Catarina, Trindade, Florianópolis, SC, 88040-900, Brazil.
Universidade Federal de Santa Catarina · BR

Funding

CAPES-PVE 052/2012CNPq 01.06.0842-00
6 · The paper itself

Abstract

Intracerebroventricular (icv) amyloid-beta (Aβ)

Indexed as

Amyloid beta-PeptidesAnimalsAntidepressive AgentsAtorvastatinBehavior, AnimalBrain-Derived Neurotrophic FactorCell DeathDepressionGlutamate-Ammonia LigaseHippocampusMaleMiceMotor ActivityNeuronsNeuroprotective AgentsPeptide FragmentsAmyloid beta-Peptidesamyloid beta-protein (1-40)Antidepressive AgentsAtorvastatinBrain-Derived Neurotrophic Factorbrain-derived neurotrophic factor precursorGlutamate-Ammonia LigaseNeuroprotective AgentsPeptide FragmentsProtein PrecursorsAtorvastatinAβ1–40BDNFDepressive-likeNeuroprotectionp11tPA

Identifiers

PMID27709490
OpenAlexW2529409407

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.