Evidence map›Paper›PMID 27709185›Full record

ArticleChemical communications (Cambridge, England)2016

Assessing the intracellular fate of rhodium(ii) complexes.

Matthew B Minus, Marci K Kang, Sarah E Knudsen, Wei Liu, Michael J Krueger, Morgen L Smith, Michele S Redell, Zachary T Ball

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical communications (Cambridge, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matthew B MinusDepartment of Chemistry, Rice University, Houston, Texas 77005, USA. zb1@rice.edu.
Marci K KangDepartment of Chemistry, Rice University, Houston, Texas 77005, USA. zb1@rice.edu.
Sarah E KnudsenDepartment of Chemistry, Rice University, Houston, Texas 77005, USA. zb1@rice.edu.
Wei LiuTexas Children's Cancer Center, Baylor College of Medicine, Houston, TX, USA.
Michael J KruegerTexas Children's Cancer Center, Baylor College of Medicine, Houston, TX, USA.
Morgen L SmithDepartment of Chemistry, Rice University, Houston, Texas 77005, USA. zb1@rice.edu.
Michele S RedellTexas Children's Cancer Center, Baylor College of Medicine, Houston, TX, USA.
Zachary T BallDepartment of Chemistry, Rice University, Houston, Texas 77005, USA. zb1@rice.edu.

Funding

Potent organometallic inhibitors of Signal Transducer and Activator of TranscriptR21CA170625 · NCI · RICE UNIVERSITY · PI BALL, ZACHARY THOMAS · 2012 to 2013
$371k
Rhodium(II)-based inhibitors for STAT family oncoproteinsF31CA180696 · NCI · RICE UNIVERSITY · PI MINUS, MATTHEW · 2013 to 2015
$99k
NCI NIH HHS F31 CA180696NCI NIH HHS R21 CA170625
6 · The paper itself

Abstract

Rhodium(ii)-fluorophore conjugates have strong rhodium-based fluorescence quenching that can be harnessed to report on a conjugate's cellular uptake and the intracellular decomposition rate. Information gleened from this study allowed the design of an improved STAT3 metalloinhibitor.

Identifiers

PMID27709185
PMCPMC5076564

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.