Evidence map›Paper›PMID 27709137›Full record

ReviewBiomaterials science2016

Recent trends on hydrogel based drug delivery systems for infectious diseases.

Arti Vashist, Ajeet Kaushik, Atul Vashist, Rahul Dev Jayant, Asahi Tomitaka, Sharif Ahmad, Y K Gupta, Madhavan Nair

Abstract readReview
In one paragraph

Review in Biomaterials science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
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  11. The role of nanotechnology in the treatment of viral infections.Therapeutic advances in infectious disease · 2017
    Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Arti VashistCenter of Personalized Nanomedicine, Institute of Neuroimmune Pharmacology, Department of Immunology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL-33199, USA. avashist@fiu.edu nairm@fiu.edu.
Ajeet KaushikCenter of Personalized Nanomedicine, Institute of Neuroimmune Pharmacology, Department of Immunology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL-33199, USA. avashist@fiu.edu nairm@fiu.edu.
Atul VashistDepartment of Biotechnology, All India Institute of Medical Sciences, New Delhi, 110029, India.
Rahul Dev JayantCenter of Personalized Nanomedicine, Institute of Neuroimmune Pharmacology, Department of Immunology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL-33199, USA. avashist@fiu.edu nairm@fiu.edu.
Asahi TomitakaCenter of Personalized Nanomedicine, Institute of Neuroimmune Pharmacology, Department of Immunology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL-33199, USA. avashist@fiu.edu nairm@fiu.edu.
Sharif AhmadMaterials Research Laboratory, Department of Chemistry, New Delhi, 110025, India.
Y K GuptaDepartment of Pharmacology, All India Institute of Medical Sciences, New Delhi, 110029, India.
Madhavan NairCenter of Personalized Nanomedicine, Institute of Neuroimmune Pharmacology, Department of Immunology, Herbert Wertheim College of Medicine, Florida International University, Miami, FL-33199, USA. avashist@fiu.edu nairm@fiu.edu.

Funding

Nanotechnology Based Gene Editing to Eradicate HIV Brain Reservoir in Drug AbusersR01DA042706 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI KHALILI, KAMEL, NAIR, MADHAVAN P. · 2016 to 2020
$3.2M
Polydrug Nanocarrier to Treat Opiate Addiction and HIV DiseaseR01DA027049 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI NAIR, MADHAVAN P. · 2009 to 2014
$3.1M
To evaluate the role of cannabinoid signaling during the comorbidity of HIV and Alzheimer¿s disease in the context of HIV-associated cognitive disordersR01DA040537 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI NAIR, MADHAVAN P. · 2015 to 2019
$3.0M
Cocaine in the Neuropathogenesis of HIV infection: Role of HDAC2R01DA034547 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI NAIR, MADHAVAN P. · 2013 to 2018
$1.8M
Multifunctional Nanocarrier to Eradicate HIV from latently infected CNS cells andR01DA037838 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI NAIR, MADHAVAN P. · 2014 to 2018
$1.8M
Novel Magneto-Electric Nanodelivery of Drugs to Eradicate HIV from CNSR21MH101025 · NIMH · FLORIDA INTERNATIONAL UNIVERSITY · PI NAIR, MADHAVAN P. · 2013 to 2014
$388k
NIDA NIH HHS R01 DA027049NIDA NIH HHS R01 DA034547NIDA NIH HHS R01 DA037838NIDA NIH HHS R01 DA040537NIDA NIH HHS R01 DA042706NIMH NIH HHS R21 MH101025
6 · The paper itself

Abstract

Since centuries, the rapid spread and cure of infectious diseases have been a major concern to the progress and survival of humans. These diseases are a global burden and the prominent cause for worldwide deaths and disabilities. Nanomedicine has emerged as the most excellent tool to eradicate and halt their spread. Various nanoformulations (NFs) using advanced nanotechnology are in demand. Recently, hydrogel and nanogel based drug delivery devices have posed new prospects to simulate the natural intelligence of various biological systems. Owing to their unique porous interpenetrating network design, hydrophobic drug incorporation and stimulus sensitivity hydrogels owe excellent potential as targeted drug delivery systems. The present review is an attempt to highlight the recent trends of hydrogel based drug delivery systems for the delivery of therapeutic agents and diagnostics for major infectious diseases including acquired immune deficiency syndrome (AIDS), malaria, tuberculosis, influenza and ebola. Future prospects and challenges are also described.

Indexed as

HydrogelsCommunicable DiseasesDrug Delivery SystemsHumansNanomedicineNanoparticlesHydrogels

Identifiers

PMID27709137
PMCPMC5162423

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.