ArticleActa pharmaceutica Sinica. B2016
Role of farnesoid X receptor in establishment of ontogeny of phase-I drug metabolizing enzyme genes in mouse liver.
Article in Acta pharmaceutica Sinica. B, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Targeting farnesoid X receptor as aging intervention therapy.Acta pharmaceutica Sinica. B · 2025Article
- The N-terminal domain of gasdermin D induces liver fibrosis by reprogrammed lipid metabolism.Animal models and experimental medicine · 2025Article
- Uncovering the roles of dihydropyrimidine dehydrogenase in fatty-acid induced steatosis using human cellular models.Scientific reports · 2022Article
- Article
- Fxr signaling and microbial metabolism of bile salts in the zebrafish intestine.Science advances · 2021Article
- Effects of total parenteral nutrition on drug metabolism gene expression in mice.Acta pharmaceutica Sinica. B · 2020Article
- Ablation of gut microbiota alleviates obesity-induced hepatic steatosis and glucose intolerance by modulating bile acid metabolism in hamsters.Acta pharmaceutica Sinica. B · 2019Article
- Combined obeticholic acid and apoptosis inhibitor treatment alleviates liver fibrosis.Acta pharmaceutica Sinica. B · 2019Article
- RNA Sequencing Reveals Age and Species Differences of Constitutive Androstane Receptor-Targeted Drug-Processing Genes in the Liver.Drug metabolism and disposition: the biological fate of chemicals · 2017Article
- Role of Farnesoid X Receptor in the Determination of Liver Transcriptome during Postnatal Maturation in Mice.Nuclear receptor research · 2017Article
- Advanced knowledge in drug metabolism and pharmacokinetics.Acta pharmaceutica Sinica. B · 2016Article
- Regulation of bile acid metabolism-related signaling pathways by gut microbiota in diseases.Journal of Zhejiang University. Science. BReview
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
The expression of phase-I drug metabolizing enzymes in liver changes dramatically during postnatal liver maturation. Farnesoid X receptor (FXR) is critical for bile acid and lipid homeostasis in liver. However, the role of FXR in regulating ontogeny of phase-I drug metabolizing genes is not clear. Hence, we applied RNA-sequencing to quantify the developmental expression of phase-I genes in both
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Registered trials
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