ReviewTremor and other hyperkinetic movements (New York, N.Y.)2016
Post-hypoxic Myoclonus: Current Concepts, Neurophysiology, and Treatment.
Review in Tremor and other hyperkinetic movements (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- European Resuscitation Council and European Society of Intensive Care Medicine guidelines 2025: post-resuscitation care.Intensive care medicine · 2025Guideline
- Myoclonus as a neurologic manifestation of hypoglycemia in dogs.Journal of veterinary internal medicine · 2026Article
- Lance-Adams syndrome following suicidal hanging: A rare complication initially misdiagnosed as dissociative motor disorder.Indian journal of psychiatry · 2026Article
- Treatment, Diagnostic Approach, and Long-Term Outcomes of Lance-Adams Syndrome.Neurocritical care · 2026Article
- Transient Postoperative Myoclonus Following Hypothermic Circulatory Arrest.Ochsner journal · 2026Article
- Post-Hypoxic Myoclonus and Deep Brain Stimulation. Experience from a Small Patient Cohort and Literature Review Highlighting Variable Outcomes.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Review
- Lance-Adams Syndrome: An Updated Review of a Rare Post-Hypoxic Complication.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025Review
- Lance-Adams syndrome or chronic post-hypoxic myoclonus in adults: a systematic literature review.Brain communications · 2025Review
- Status Epilepticus and Coexisting Nonepileptic Atypical Abdominal Myoclonus in a Preterm Neonate with Hypoxic Ischemic Encephalopathy: A Case Report.Acta medica Philippina · 2025Article
- The Use of Perampanel in the Treatment of Lance-Adams Syndrome.Journal of epilepsy research · 2024Article
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- A Reappraisal on cortical myoclonus and brief Remarks on myoclonus of different Origins.Clinical neurophysiology practice · 2024Review
- Post hypoxic myoclonus: A tale of two minds.Epilepsy & behavior reports · 2023Article
- A Rare Case of Lance-Adams Syndrome: Status Post-Successful Cardiopulmonary Resuscitation.Cureus · 2022Article
- A Case of Lance Adams Syndrome in a Patient with Attempted Hanging.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022Article
- Successful Control of Intractable Myoclonus in a Patient With Hypoxic Brain Injury After Intrathecal Baclofen Therapy: A Case Report.Brain & NeuroRehabilitation · 2022Article
- Lance Adams syndrome: two cases report and literature review.The Journal of international medical research · 2022Review
- Disorders of Movement due to Acquired and Traumatic Brain Injury.Current physical medicine and rehabilitation reports · 2022Review
- A Case of Lance-Adams Syndrome with Mixed Cortical and Reticular Reflex Myoclonus.Tremor and other hyperkinetic movements (New York, N.Y.) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMyoclonus may occur after hypoxia. In 1963, Lance and Adams described persistent myoclonus with other features after hypoxia. However, myoclonus occurring immediately after hypoxia may demonstrate different syndromic features from classic Lance-Adams syndrome (LAS). The aim of this review is to provide up-to-date information about the spectrum of myoclonus occurring after hypoxia with emphasis on neurophysiological features.
methodsA literature search was performed on PubMed database from 1960 to 2015. The following search terms were used: "myoclonus," "post anoxic myoclonus," "post hypoxic myoclonus," and "Lance Adams syndrome." The articles describing clinical features, neurophysiology, management, and prognosis of post-hypoxic myoclonus cases were included for review.
resultsSeveral reports in the literature were separated clinically into "acute post-hypoxic myoclonus," which occurred within hours of severe hypoxia, and "chronic post-hypoxic myoclonus," which occurred with some recovery of mental status as the LAS. Acute post-hypoxic myoclonus was generalized in the setting of coma. Chronic post-hypoxic myoclonus presented as multifocal cortical action myoclonus that was significantly disabling. There was overlap of neurophysiological findings for these two syndromes but also different features. Treatment options for these two distinct clinical-neurophysiologic post-hypoxic myoclonus syndromes were approached differently. DISCUSSION: The review of clinical and neurophysiological findings suggests that myoclonus after hypoxia manifests in one or a combination of distinct syndromes: acute and/or chronic myoclonus. The mechanism of post-hypoxic myoclonus may arise either from cortical and/or subcortical structures. More research is needed to clarify mechanisms and treatment of post-hypoxic myoclonus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.