ArticleBiomaterials research2016
Polypyrrole-incorporated conductive hyaluronic acid hydrogels.
Article in Biomaterials research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling.FEBS open bio · 2026Review
- Immunoengineering External Field Responsive Biomaterials for Tissue Repair and Regeneration.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Simultaneous Cross-Linking and Nanoparticle Anchoring by Dialdehyde Cellulose in Injectable Composite Chitosan/Polypyrrole Hydrogels.ACS applied bio materials · 2026Article
- Conductive biological materials for in vitro models: properties and sustainability implications.In vitro models · 2025Article
- Development of Covalently Functionalized Alginate-Pyrrole and Polypyrrole-Alginate Nanocomposites as 3D Printable Electroconductive Bioinks.Materials (Basel, Switzerland) · 2025Article
- Freeze-Dried Porous Collagen Scaffolds for the Repair of Volumetric Muscle Loss Injuries.ACS biomaterials science & engineering · 2025Article
- Electrically conductive "SMART" hydrogels for on-demand drug delivery.Asian journal of pharmaceutical sciences · 2025Review
- Freeze-dried porous collagen scaffolds for the repair of volumetric muscle loss injuries.bioRxiv : the preprint server for biology · 2024Article
- Decoupling the Influence of Poly(3,4-Ethylenedioxythiophene)-Collagen Composite Characteristics on Cell Stemness.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Seamless Integration of Conducting Hydrogels in Daily Life: From Preparation to Wearable Application.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Electroactive Polymers for On-Demand Drug Release.Advanced healthcare materials · 2024Review
- Fabrication and desired properties of conductive hydrogel dressings for wound healing.RSC advances · 2023Review
- Instant formation of horizontally ordered nanofibrous hydrogel films and direct investigation of peculiar neuronal cell behaviors atop.Biomaterials research · 2023Article
- 3D-Printed Electroactive Hydrogel Architectures with Sub-100 µm Resolution Promote Myoblast Viability.Macromolecular bioscience · 2022Article
- New approach to prepare cytocompatible 3D scaffolds via the combination of sodium hyaluronate and colloidal particles of conductive polymers.Scientific reports · 2022Article
- Irreversible and Self-Healing Electrically Conductive Hydrogels Made of Bio-Based Polymers.International journal of molecular sciences · 2022Review
- Conductive Collagen-Based Hydrogel Combined With Electrical Stimulation to Promote Neural Stem Cell Proliferation and Differentiation.Frontiers in bioengineering and biotechnology · 2022Article
- Conductive Bioimprint Using Soft Lithography Technique Based on PEDOT:PSS for Biosensing.Bioengineering (Basel, Switzerland) · 2021Article
- Conductive Polymeric-Based Electroactive Scaffolds for Tissue Engineering Applications: Current Progress and Challenges from Biomaterials and Manufacturing Perspectives.International journal of molecular sciences · 2021Review
- Development and Characterization of Conducting-Polymer-Based Hydrogel Dressing for Wound HealingTurkish journal of pharmaceutical sciences · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHydrogels that possess hydrophilic and soft characteristics have been widely used in various biomedical applications, such as tissue engineering scaffolds and drug delivery. Conventional hydrogels are not electrically conductive and thus their electrical communication with biological systems is limited.
methodTo create electrically conductive hydrogels, we fabricated composite hydrogels of hyaluronic acid and polypyrrole. In particular, we synthesized and used pyrrole-hyaluronic acid-conjugates and further chemically polymerized polypyrrole with the conjugates for the production of conductive hydrogels that can display suitable mechanical and structural properties.
resultsVarious characterization methods, using a rheometer, a scanning electron microscope, and an electrochemical analyzer, revealed that the PPy/HA hydrogels were soft and conductive with ~ 3 kPa Young's modulus and ~ 7.3 mS/cm conductivity. Our preliminary in vitro culture studies showed that fibroblasts were well attached and grew on the conductive hydrogels.
conclusionThese new conductive hydrogels will be greatly beneficial in fields of biomaterials in which electrical properties are important such as tissue engineering scaffolds and prosthetic devices.
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