Evidence map›Paper›PMID 27708854›Full record

ArticleESC heart failure2015

Heterogeneous responses of systolic and diastolic left ventricular function to exercise in patients with heart failure and preserved ejection fraction.

Mario Kasner, David Sinning, Jil Lober, Heiner Post, Alan G Fraser, Burkert Pieske, Daniel Burkhoff, Carsten Tschöpe

Open access · goldAbstract read
In one paragraph

Article in ESC heart failure, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Mario KasnerDepartment of Cardiology Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin Hindenburgdamm 30 Berlin Germany.
David SinningDepartment of Cardiology Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin Hindenburgdamm 30 Berlin Germany.
Jil LoberDepartment of Cardiology Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin Hindenburgdamm 30 Berlin Germany.
Heiner PostDepartment of Cardiology Charité-Universitätsmedizin Berlin, Campus Virchow Berlin Germany.
Alan G FraserWales Heart Research Institute, Cardiff University Cardiff UK.
Burkert PieskeDepartment of CardiologyCharité-Universitätsmedizin Berlin, Campus VirchowBerlinGermany; Germany Centre for Cardiovascular Research (DZHK)BerlinGermany.
Daniel BurkhoffDivision of Cardiology Columbia University New York NY USA.
Carsten TschöpeDepartment of CardiologyCharité-Universitätsmedizin Berlin, Campus VirchowBerlinGermany; Germany Centre for Cardiovascular Research (DZHK)BerlinGermany; Berlin-Brandenburg Center for Regenerative TherapiesCharité-Universitätsmedizin Berlin, Campus VirchowBerlinGermany.
Charité - Universitätsmedizin Berlin · DECardiff University · GBColumbia University Irving Medical Center · USFranklin University · USGerman Centre for Cardiovascular Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis study aimed to evaluate ventricular diastolic properties using three-dimensional echocardiography and tissue Doppler imaging at rest and during exercise in heart failure with preserved ejection fraction (HFpEF) patients with borderline evidence of diastolic dysfunction at rest. METHODS AND

resultsResults obtained from 52 HFpEF patients (left ventricular ejection fraction ≥ 50%) identified on the basis of heart failure symptoms and

conclusionThree-dimensional stress echocardiography may allow non-invasive analysis of changes in cardiac output that can differentiate HFpEF patients with an inappropriate increase or a fall in SV during exercise. Impaired systolic or diastolic reserve can contribute to these haemodynamic abnormalities, which may arise from different underlying pathophysiologic mechanisms.

Indexed as

3D EchocardiographyDiastoleExerciseHaemodynamicsHeart Failure

Identifiers

PMID27708854
PMCPMC5042029
OpenAlexW2102688445

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.