Evidence map›Paper›PMID 27708853›Full record

ArticleESC heart failure2015

Biological variation of the cardiac index in patients with stable chronic heart failure: inert gas rebreathing compared with impedance cardiography.

Tobias Täger, Hanna Fröhlich, Jennifer Franke, Karen Slottje, Andrea Horsch, Dietmar Zdunek, Georg Hess, Andreas Dösch, Hugo A Katus, Frank H Wians and 1 more

Open access · goldAbstract read
In one paragraph

Article in ESC heart failure, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Biological variation of extracellular matrix biomarkers in patients with stable chronic heart failure.Clinical research in cardiology : official journal of the German Cardiac Society · 2017
    Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Tobias TägerDepartment of Cardiology, Angiology, and Pulmology University of Heidelberg Heidelberg Germany.
Hanna FröhlichDepartment of Cardiology, Angiology, and Pulmology University of Heidelberg Heidelberg Germany.
Jennifer FrankeDepartment of Cardiology, Angiology, and Pulmology University of Heidelberg Heidelberg Germany.
Karen SlottjeDepartment of Cardiology, Angiology, and Pulmology University of Heidelberg Heidelberg Germany.
Andrea HorschRoche Diagnostics International AG Risch-Rotkreuz Switzerland.
Dietmar ZdunekRoche Diagnostics International AG Risch-Rotkreuz Switzerland.
Georg HessRoche Diagnostics International AG Risch-Rotkreuz Switzerland.
Andreas DöschDepartment of Cardiology, Angiology, and Pulmology University of Heidelberg Heidelberg Germany.
Hugo A KatusDepartment of Cardiology, Angiology, and Pulmology University of Heidelberg Heidelberg Germany.
Frank H WiansPark University Ext LAFB San Antonio TX USA.
Lutz FrankensteinDepartment of Cardiology, Angiology, and Pulmology University of Heidelberg Heidelberg Germany.ORCID 0000-0001-7216-1004
Heidelberg University · DERoth and Rau (Germany) · DEPark University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsIn chronic heart failure (CHF), changes in cardiac function define the course of the disease. The cardiac index (CI) is the most adequate indicator of cardiac function. Interpretation of serial CI measurements, however, requires knowledge of the biological variation of CI. Because measurements of CI can be confounded by the clinical situation or the method applied, biological variation might be subject to the same confounders. METHODS AND

resultsWe prospectively included 50 CHF patients who met rigid criteria for clinical stability. CI was measured by both inert gas rebreathing (IGR) and impedance cardiography (ICG) in weekly intervals over 3 weeks-each measurement performed at rest (IGR

conclusionNon-invasive measurements of CI are stable over time. Measurement modalities for CI, however, are not interchangeable. Biological variation is less pronounced when obtained by ICG. The influence of low-level exercise on stability of CI depends on the measurement modality.

Indexed as

Biological variationCardiac indexChronic heart failureImpedance cardiographyInert gas rebreathing

Identifiers

PMID27708853
PMCPMC5032993
OpenAlexW1556038437

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.