ArticleFrontiers in zoology2016
The cephalopod arm crown: appendage formation and differentiation in the Hawaiian bobtail squid
Article in Frontiers in zoology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- The vertebrate yolk sac: evolutionary origins and current advances in in vitro models.Development (Cambridge, England) · 2026Review
- Integrated morphological and transcriptomic analysis of sucker development inAnimal cells and systems · 2026Article
- Characterization of C2H2 superfamily expansions in cephalopods and their contribution to nervous system evolution.iScience · 2025Article
- Molecular and Morphological Circuitry of the Octopus Sucker Ganglion.The Journal of comparative neurology · 2025Article
- Neuronal segmentation in cephalopod arms.Nature communications · 2025Article
- Postembryonic development and lifestyle shift in the commensal ribbon worm.Frontiers in zoology · 2024Article
- A lasting symbiosis: how the Hawaiian bobtail squid finds and keeps its bioluminescent bacterial partner.Nature reviews. Microbiology · 2021Review
- Potential evidence of peripheral learning and memory in the arms of dwarf cuttlefish, Sepia bandensis.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2021Article
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- Pattern of sucker development in cuttlefishes.Frontiers in zoology · 2020Article
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- Genomic signatures of G-protein-coupled receptor expansions reveal functional transitions in the evolution of cephalopod signal transduction.Proceedings. Biological sciences · 2019Article
- Molecular Determinants of Cephalopod Muscles and Their Implication in Muscle Regeneration.Frontiers in cell and developmental biology · 2017Review
- The Pax gene family: Highlights from cephalopods.PloS one · 2017Article
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCephalopods are a highly derived class of molluscs that adapted their body plan to a more active and predatory lifestyle. One intriguing adaptation is the modification of the ventral foot to form a bilaterally symmetric arm crown, which constitutes a true morphological novelty in evolution. In addition, this structure shows many diversifications within the class of cephalopods and therefore offers an interesting opportunity to study the molecular underpinnings of the emergence of phenotypic novelties and their diversification. Here we use the sepiolid
resultsWe show that the morphological formation of the cephalopod appendages occurs during distinct phases, including outgrowth, elongation, and tissue differentiation. Early outgrowth is characterized by uniform cell proliferation, while the elongation of the appendages initiates tissue differentiation. The latter progresses in a gradient from proximal to distal, whereas cell proliferation becomes restricted to the distal-most end of the arm. Differences in the formation of arms and tentacles exist, with the tentacles showing an expedite growth rate and higher complexity at younger stages.
conclusionThe early outgrowth and differentiation of the
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