Evidence map›Paper›PMID 27708610›Full record

ArticleFrontiers in neurology2016

Patterns of Co-Occurring Gray Matter Concentration Loss across the Huntington Disease Prodrome.

Jennifer Ashley Ciarochi, Vince D Calhoun, Spencer Lourens, Jeffrey D Long, Hans J Johnson, H Jeremy Bockholt, Jingyu Liu, Sergey M Plis, Jane S Paulsen, Jessica A Turner and 1 more

Abstract read
In one paragraph

Article in Frontiers in neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jennifer Ashley CiarochiNeuroscience Institute, Georgia State University , Atlanta, GA , USA.
Vince D CalhounThe Mind Research Network, Albuquerque, NM, USA; Department of Electrical and Computer Engineering, University of New Mexico, Albuquerque, NM, USA.
Spencer LourensDepartment of Psychiatry, University of Iowa , Iowa City, IA , USA.
Jeffrey D LongDepartment of Psychiatry, University of Iowa, Iowa City, IA, USA; Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, IA, USA.
Hans J JohnsonDepartment of Psychiatry, University of Iowa, Iowa City, IA, USA; Department of Electrical and Computer Engineering, University of Iowa, Iowa City, IA, USA.
H Jeremy BockholtDepartment of Psychiatry, University of Iowa , Iowa City, IA , USA.
Jingyu LiuThe Mind Research Network , Albuquerque, NM , USA.
Sergey M PlisThe Mind Research Network , Albuquerque, NM , USA.
Jane S PaulsenDepartment of Psychiatry, University of Iowa, Iowa City, IA, USA; Department of Neurology, University of Iowa, Iowa City, IA, USA; Department of Psychology, University of Iowa, Iowa City, IA, USA.
Jessica A TurnerNeuroscience Institute, Georgia State University, Atlanta, GA, USA; The Mind Research Network, Albuquerque, NM, USA.
PREDICT-HD Investigators and Coordinators of the Huntington Study Group

Funding

University of Iowa Clinical and Translational Science ProgramUL1TR000442 · NCATS · UNIVERSITY OF IOWA · PI ROSENTHAL, GARY E · 2012 to 2013
$10.0M
Multivariate methods for identifying multitask/multimodal brain imaging biomarkersR01EB006841 · NIBIB · THE MIND RESEARCH NETWORK · PI VINCE D CALHOUN, Sergey Plis · 2007 to 2026
$9.8M
Unified multivariate data-driven solutions for static and dynamic brain connectivityR01EB020407 · NIBIB · THE MIND RESEARCH NETWORK · PI ADALI, TULAY, CALHOUN, VINCE D · 2015 to 2018
$2.7M
Imaging and Genetics in Huntington's DiseaseU01NS082074 · NINDS · THE MIND RESEARCH NETWORK · PI CALHOUN, VINCE D, TURNER, JESS · 2013 to 2015
$1.4M
NCATS NIH HHS UL1 TR000442NIBIB NIH HHS R01 EB006841NIBIB NIH HHS R01 EB020407NINDS NIH HHS U01 NS082074
6 · The paper itself

Abstract

Huntington disease (HD) is caused by an abnormally expanded cytosine-adenine-guanine (CAG) trinucleotide repeat in the

Indexed as

disease progressiongray matter concentrationhumansmagnetic resonance imagingmovement disordersmultivariate methodsprodromal symptoms

Identifiers

PMID27708610
PMCPMC5030293

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.