ArticleThe American journal of tropical medicine and hygiene2016
Epidemiology of Plasmodium vivax in Indonesia.
Article in The American journal of tropical medicine and hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association of G6PD status and haemolytic anaemia in patients receiving anti-malarial agents: a systematic review and meta-analysis.Malaria journal · 2023Pooled it
- Trial
- The household economic burden of human-only and zoonotic malaria, compared to other causes of acute febrile illness in Indonesia.BMJ global health · 2026Article
- Serological evidence of continued exposure toFrontiers in microbiology · 2025Article
- Whole blood transcriptomics analysis of Indonesians reveals translocated and pathogenic microbiota in blood.PloS one · 2025Article
- Characterizing the genetic diversity and population structure of Plasmodium knowlesi in Aceh Province, Indonesia.PloS one · 2025Article
- Plasmodium vivax in Children: Hidden Burden and Conspicuous Challenges, a Narrative Review.Infectious diseases and therapy · 2023Review
- The history and current epidemiology of malaria in Kalimantan, Indonesia.Malaria journal · 2022Review
- Tafenoquine forThe Indian journal of medical research · 2021Review
- Prevalence of Glucose 6-Phosphate Dehydrogenase Variants in Malaria-Endemic Areas of South Central Timor, Eastern Indonesia.The American journal of tropical medicine and hygiene · 2020Article
- Performance comparison of two malaria rapid diagnostic test with real time polymerase chain reaction and gold standard of microscopy detection method.Infectious disease reports · 2020Article
- The Burden of Malaria Incidence in Subaim, East Halmahera, North Maluku, Indonesia in 2016.Open access Macedonian journal of medical sciences · 2019Article
- Current Status of Parasite Infections in Indonesia: A Literature Review.The Korean journal of parasitology · 2019Review
- Epidemiology ofThe American journal of tropical medicine and hygiene · 2018Article
- Postmalaria elimination: Overview of recurrent malaria cases in Riau Province, Indonesia.Tropical parasitologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Endemic malaria occurs across much of the vast Indonesian archipelago. All five species of Plasmodium known to naturally infect humans occur here, along with 20 species of Anopheles mosquitoes confirmed as carriers of malaria. Two species of plasmodia cause the overwhelming majority and virtually equal shares of malaria infections in Indonesia: Plasmodium falciparum and Plasmodium vivax The challenge posed by P. vivax is especially steep in Indonesia because chloroquine-resistant strains predominate, along with Chesson-like strains that relapse quickly and multiple times at short intervals in almost all patients. Indonesia's hugely diverse human population carries many variants of glucose-6-phosphate dehydrogenase (G6PD) deficiency, most of them exhibiting severely impaired enzyme activity. Therefore, the patients most likely to benefit from primaquine therapy by preventing aggressive relapse, may also be most likely to suffer harm without G6PD deficiency screening. Indonesia faces the challenge of controlling and eventually eliminating malaria across > 13,500 islands stretching > 5,000 km and an enormous diversity of ecological, ethnographic, and socioeconomic settings, and extensive human migrations. This article describes the occurrence of P. vivax in Indonesia and the obstacles faced in eliminating its transmission.
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Registered trials
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