ArticleProceedings of the National Academy of Sciences of the United States of America2016
Interfibrillar stiffening of echinoderm mutable collagenous tissue demonstrated at the nanoscale.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Mechanical Training-Induced Restructuring Enables Self-Extendability and Mechanical Consistency in Organohydrogels.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Mechanically adaptive materials with tunable stiffness for biomedical devices: Mechanisms, applications, and perspectives.Materials today. Bio · 2026Review
- Mineralized sclerites in the gorgonian coralProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Autonomous codesign and fabrication of multistimuli-responsive material systems.Science advances · 2025Article
- Article
- A tough soft-hard interface in the human knee joint driven by multiscale toughening mechanisms.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Matrikines of Sea Cucumbers: Structure, Biological Activity and Mechanisms of Action.International journal of molecular sciences · 2024Review
- A starfish-inspired 4D self-healing morphing structure.Scientific reports · 2024Article
- Construction of Reconfigurable and Polymorphic DNA Origami Assemblies with Coiled-Coil Patches and Patterns.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Mutable Collagenous Tissue: A Concept Generator for Biomimetic Materials and Devices.Marine drugs · 2024Review
- Is Stress Relaxation in Sea Cucumber Dermis Chemoelastic?Marine drugs · 2023Article
- Article
- Extracellular Matrix of Echinoderms.Marine drugs · 2023Review
- Antitumor Properties of Matrikines of Different Origins: Prospects and Problems of Their Application.International journal of molecular sciences · 2023Review
- Silk Fibroin-Based Shape-Memory Organohydrogels with Semicrystalline Microinclusions.ACS applied bio materials · 2023Article
- Review
- Possible Mechanisms of Stiffness Changes Induced by Stiffeners and Softeners in Catch Connective Tissue of Echinoderms.Marine drugs · 2023Review
- Cryogelation reactions and cryogels: principles and challenges.Turkish journal of chemistry · 2023Article
- Biomaterials and Bioactive Natural Products from Marine Invertebrates: From Basic Research to Innovative Applications.Marine drugs · 2022Review
- Investigating the Fibrillar Ultrastructure and Mechanics in Keloid Scars Using In Situ Synchrotron X-ray Nanomechanical Imaging.Materials (Basel, Switzerland) · 2022Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mutable collagenous tissue (MCT) of echinoderms (e.g., sea cucumbers and starfish) is a remarkable example of a biological material that has the unique attribute, among collagenous tissues, of being able to rapidly change its stiffness and extensibility under neural control. However, the mechanisms of MCT have not been characterized at the nanoscale. Using synchrotron small-angle X-ray diffraction to probe time-dependent changes in fibrillar structure during in situ tensile testing of sea cucumber dermis, we investigate the ultrastructural mechanics of MCT by measuring fibril strain at different chemically induced mechanical states. By measuring a variable interfibrillar stiffness (E
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