Evidence map›Paper›PMID 27707893›Full record

ArticleThe Journal of infectious diseases2016

More Challenges From Ebola: Infection of the Central Nervous System.

Gary Wong, Xiangguo Qiu, Yuhai Bi, Pierre Formenty, Armand Sprecher, Michael Jacobs, George F Gao, Gary Kobinger

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Characterization of Atypical Ebola Virus Disease in Ferrets.bioRxiv : the preprint server for biology · 2026
    Article
  3. Human Riboviruses: A Comprehensive Study.Journal of molecular evolution · 2025
    Review
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  5. Article
  6. Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 8 countries.

Gary WongCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada Department of Medical Microbiology.
Xiangguo QiuSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada Department of Medical Microbiology.
Yuhai BiCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences Shenzhen Key Laboratory of Pathogen and Immunity, Shenzhen Third People's Hospital, China.
Pierre FormentyDepartment of Pandemic and Epidemic Diseases, World Health Organization, Geneva, Switzerland.
Armand SprecherMédecins Sans Frontières, Operational Center of Brussels, Belgium.
Michael JacobsDepartment of Infection, Royal Free London NHS Foundation Trust, London, United Kingdom.
George F GaoCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences Office of the Director General, Chinese Center for Disease Control and Prevention, Beijing Shenzhen Key Laboratory of Pathogen and Immunity, Shenzhen Third People's Hospital, China.
Gary KobingerSpecial Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada Department of Medical Microbiology Department of Immunology, University of Manitoba, Winnipeg, Canada Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia.
Czech Academy of Sciences, Institute of Microbiology · CZChinese Academy of Sciences · CNMédecins Sans Frontières · BEPublic Health Agency of Canada · CARoyal Free London NHS Foundation Trust · GBUniversity of Manitoba · CAWorld Health Organization · CH

Funding

CIHRWorld Health Organization 001
6 · The paper itself

Abstract

Cases of relapsed Ebola virus disease involving symptoms in the central nervous system are reminiscent of our past observations with some nonhuman primates (NHPs) that survived acute Ebola virus infection. We document our findings in detail here and suggest that this phenomenon can be further investigated in NHPs.

Indexed as

AnimalsCentral Nervous SystemEbolavirusHemorrhagic Fever, EbolaHumansRecurrencecentral nervous systemEbola virusnonhuman primatesrelapse; outbreak

Identifiers

PMID27707893
PMCPMC5050477
OpenAlexW2528174915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.