Evidence map›Paper›PMID 27707836›Full record

Trial reportBMJ open2016

Strength Training for Adolescents with cerebral palsy (STAR): study protocol of a randomised controlled trial to determine the feasibility, acceptability and efficacy of resistance training for adolescents with cerebral palsy.

Jennifer M Ryan, Nicola Theis, Cherry Kilbride, Vasilios Baltzopoulos, Charlie Waugh, Adam Shortland, Grace Lavelle, Marika Noorkoiv, Wendy Levin, Thomas Korff

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Jennifer M RyanCollege of Health and Life Sciences, Brunel University London, London, UK.
Nicola TheisSchool of Sport, Health and Applied Science, St. Mary's University, Twickenham, UK.
Cherry KilbrideCollege of Health and Life Sciences, Brunel University London, London, UK.
Vasilios BaltzopoulosCollege of Health and Life Sciences, Brunel University London, London, UK.
Charlie WaughDepartment of Physical Therapy, University of British Columbia, Vancouver, British Columbia, Canada.
Adam ShortlandOne Small Step Gait Laboratory, Guy's Hospital, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
Grace LavelleCollege of Health and Life Sciences, Brunel University London, London, UK.
Marika NoorkoivCollege of Health and Life Sciences, Brunel University London, London, UK.
Wendy LevinDepartment of Physiotherapy, Royal Free London NHS Foundation Trust, Swiss Cottage School Development and Research Centre, London, UK.
Thomas KorffCollege of Health and Life Sciences, Brunel University London, London, UK.
Brunel University of London · GBGuy's and St Thomas' NHS Foundation Trust · GBRoyal Free London NHS Foundation Trust · GBSt Mary's University Twickenham London · GBUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGait is inefficient in children with cerebral palsy, particularly as they transition to adolescence. Gait inefficiency may be associated with declines in gross motor function and participation among adolescents with cerebral palsy. Resistance training may improve gait efficiency through a number of biomechanical and neural mechanisms. The aim of the Strength Training for Adolescents with cerebral palsy (STAR) trial is to evaluate the effect of resistance training on gait efficiency, activity and participation in adolescents with cerebral palsy. We also aim to determine the biomechanical and neural adaptations that occur following resistance training and evaluate the feasibility and acceptability of such an intervention for adolescents with cerebral palsy. METHODS AND ANALYSIS: 60 adolescents (Gross Motor Function Classification System level I-III) will be randomised to a 10-week resistance training group or a usual care control group according to a computer-generated random schedule. The primary outcome is gait efficiency. Secondary outcomes are habitual physical activity, participation, muscle-tendon mechanics and gross motor function. General linear models will be used to evaluate differences in continuous data between the resistance training and usual care groups at 10 and 22 weeks, respectively. A process evaluation will be conducted alongside the intervention. Fidelity of the resistance training programme to trial protocol will be quantified by observations of exercise sessions. Semistructured interviews will be conducted with participants and physiotherapists following the resistance training programme to determine feasibility and acceptability of the programme. ETHICS AND DISSEMINATION: This trial has ethical approval from Brunel University London's Department of Clinical Sciences' Research Ethics Committee and the National Research Ethics Service (NRES) Committee London-Surrey Borders. The results of the trial will be submitted for publication in academic journals, presented at conferences and distributed to adolescents, families and healthcare professionals through the media with the assistance of the STAR advisory group. TRIAL REGISTRATION NUMBER: ISRCTN90378161; Pre-results.

Indexed as

Exercise TherapyGaitMuscle StrengthResistance TrainingAdolescentAdultCerebral PalsyChildExerciseHumansMuscle, SkeletalPatient Acceptance of Health CareResearch DesignSingle-Blind MethodTreatment OutcomeWalkingPAEDIATRICSQUALITATIVE RESEARCHREHABILITATION MEDICINE

Identifiers

PMID27707836
PMCPMC5073599
OpenAlexW2528982743

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.