ArticleBMJ open2016
Readmissions and mortality in delirious versus non-delirious octogenarian patients after aortic valve therapy: a prospective cohort study.
Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- A call to action for delirium research: Meta-analysis and regression of delirium associated mortality.BMC geriatrics · 2020Pooled it
- Meta-analysis of Prevalence and Risk Factors for Delirium After Transcatheter Aortic Valve Implantation.The American journal of cardiology · 2018Pooled it
- Effect of digital tools to promote hospital quality and safety on adverse events after discharge.Journal of the American Medical Informatics Association : JAMIA · 2024Trial
- Multiparametric Outcome Assessment After Transcatheter Aortic Valve Implantation-A Systematic Review.Journal of clinical medicine · 2025Review
- Anxiety and depression in patients aged 80 years and older following aortic valve therapy. A six-month follow-up study.Aging clinical and experimental research · 2023Article
- Incidence and predictors of hemodynamic compromise due to high-grade AV block after TAVI.Frontiers in cardiovascular medicine · 2023Article
- The impact of frailty on adverse outcomes after transcatheter aortic valve replacement in older adults: A retrospective cohort study.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2022Article
- Intraoperative hypotension and delirium among older adults undergoing transcatheter aortic valve replacement.Journal of the American Geriatrics Society · 2021Observational
- Delirium in older patients undergoing aortic valve replacement: incidence, predictors, and cognitive prognosis.BMC geriatrics · 2021Article
- Article
- Incidence, risk factors, and cumulative risk of delirium among ICU patients: A case-control study.International journal of nursing sciences · 2019Article
- Delirium Incidence and Functional Outcomes After Transcatheter and Surgical Aortic Valve Replacement.Journal of the American Geriatrics Society · 2019Article
- Indwelling urinary catheters, aortic valve treatment and delirium: a prospective cohort study.BMJ open · 2018Observational
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine whether postoperative delirium predicts first-time readmissions and mortality in octogenarian patients within 180 days after aortic valve therapy with surgical aortic valve replacement (SAVR) or transcatheter aortic valve implantation (TAVI), and to determine the most common diagnoses at readmission.
designProspective cohort study of patients undergoing elective SAVR or TAVI.
settingTertiary university hospital that performs all SAVRs and TAVIs in Western Norway.
participantsPatients 80+ years scheduled for SAVR or TAVI and willing to participate in the study were eligible. Those unable to speak Norwegian were excluded. Overall, 143 patients were included, and data from 136 are presented. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was a composite variable of time from discharge to first all-cause readmission or death. Secondary outcomes were all-cause first readmission alone and mortality within 180 days after discharge, and the primary diagnosis at discharge from first-time readmission. Delirium was assessed with the confusion assessment method. First-time readmissions, diagnoses and mortality were identified in hospital information registries.
resultsDelirium was identified in 56% of patients. The effect of delirium on readmissions and mortality was greatest during the first 2 months after discharge (adjusted HR 2.9 (95% CI 1.5 to 5.7)). Of 30 first-time readmissions occurring within 30 days, 24 (80%) were patients who experienced delirium. 1 patient (non-delirium group) died within 30 days after therapy. Delirious patients comprised 35 (64%) of 55 first-time readmissions occurring within 180 days. Circulatory system diseases and injuries were common causes of first-time readmissions within 180 days in delirious patients. 8 patients died 180 days after the procedure; 6 (75%) of them experienced delirium.
conclusionsDelirium in octogenarians after aortic valve therapy might be a serious risk factor for postoperative morbidity and mortality. Cardiovascular disorders and injuries were associated with first-time readmissions in these patients.
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