Evidence map›Paper›PMID 27707818›Full record

Trial reportJournal of lipid research2016

Monoacylglycerol-enriched oil increases EPA/DHA delivery to circulatory system in humans with induced lipid malabsorption conditions.

Cristina Cruz-Hernandez, Frédéric Destaillats, Sagar K Thakkar, Laurence Goulet, Emma Wynn, Dominik Grathwohl, Claudia Roessle, Sara de Giorgi, Luc Tappy, Francesca Giuffrida and 1 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of lipid research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Cristina Cruz-HernandezNestlé Research Center, 1000 Lausanne, Switzerland. Electronic address: cristina.cruz-hernandez@rdls.nestle.com.
Frédéric DestaillatsNestlé Research Center, 1000 Lausanne, Switzerland.
Sagar K ThakkarNestlé Research Center, 1000 Lausanne, Switzerland.
Laurence GouletNestlé Research Center, 1000 Lausanne, Switzerland.
Emma WynnNestlé Research Center, 1000 Lausanne, Switzerland.
Dominik GrathwohlNestlé Research Center, 1000 Lausanne, Switzerland.
Claudia RoessleNestlé Research Center, 1000 Lausanne, Switzerland.
Sara de GiorgiDepartment of Physiology, Faculty of Biology and Medicine, 1005 Lausanne, Switzerland.
Luc TappyDepartment of Physiology, Faculty of Biology and Medicine, 1005 Lausanne, Switzerland.
Francesca GiuffridaNestlé Research Center, 1000 Lausanne, Switzerland.
Vittorio GiustiUniversity of Lausanne, 1005 Lausanne, Switzerland.
Nestlé (Switzerland) · CHUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It was hypothesized that under induced lipid malabsorption/maldigestion conditions, an enriched sn-1(3)-monoacylglycerol (MAG) oil may be a better carrier for n-3 long-chain PUFAs (LC-PUFAs) compared with triacylglycerol (TAG) from fish oil. This monocentric double blinded clinical trial examined the accretion of EPA (500 mg/day) and DHA (300 mg/day) when consumed as TAG or MAG, into the erythrocytes, plasma, and chylomicrons of 45 obese (BMI ≥30 kg/m

Indexed as

AdultAnti-Obesity AgentsCell MembraneChylomicronsDocosahexaenoic AcidsDouble-Blind MethodEicosapentaenoic AcidErythrocytesFemaleFish OilsHumansLactonesLipid Metabolism DisordersMaleMiddle AgedMonoglyceridesAnti-Obesity AgentsChylomicronsDocosahexaenoic AcidsEicosapentaenoic AcidFish OilsLactonesMonoglyceridesOrlistatclinical trialsdiet effects/lipid metabolismdigestiondocosahexaenoic acideicosapentaenoic acidfatty acid/metabolismlipaselipid absorptionobeseOrlistatpolyunsaturated fatty acid

Identifiers

PMID27707818
PMCPMC5321218
OpenAlexW2527772851

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.