Evidence map›Paper›PMID 27707708›Full record

ArticleAmerican journal of physiology. Renal physiology2016

Collecting duct-specific knockout of nitric oxide synthase 3 impairs water excretion in a sex-dependent manner.

Yang Gao, Deborah Stuart, Jennifer S Pollock, Takamune Takahishi, Donald E Kohan

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Genes · 2022
    Article
  2. Article
  3. High salt intake induces collecting duct HDAC1-dependent NO signaling.American journal of physiology. Renal physiology · 2021
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. EHD4 is a novel regulator of urinary water homeostasis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2017
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Yang GaoDivision of Nephrology, University of Utah Health Sciences Center, Salt Lake City, Utah.
Deborah StuartDivision of Nephrology, University of Utah Health Sciences Center, Salt Lake City, Utah.
Jennifer S PollockDivision of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama.
Takamune TakahishiDivision of Nephrology, Vanderbilt University School of Medicine, Nashville, Tennessee; and.
Donald E KohanDivision of Nephrology, University of Utah Health Sciences Center, Salt Lake City, Utah; donald.kohan@hsc.utah.edu.
University of Utah · USUniversity of Alabama at Birmingham · USVanderbilt University · US

Funding

Generating Mouse Mutants with Diabetic NephropathyU01DK061018 · NIDDK · VANDERBILT UNIVERSITY · PI HARRIS, RAYMOND C. · 2001 to 2010
$6.1M
Vanderbilt O'Brien Mouse Kidney Physiology and Disease CenterP30DK079341 · NIDDK · VANDERBILT UNIVERSITY · PI HARRIS, RAYMOND C. · 2008 to 2013
$4.4M
Integrated control of collecting duct function and endothelin synthesisR01DK107454 · NIDDK · UNIVERSITY OF UTAH · PI KOHAN, DONALD E · 2016 to 2016
$100k
NIDDK NIH HHS P30 DK079341NIDDK NIH HHS R01 DK107454NIDDK NIH HHS U01 DK061018
6 · The paper itself

Abstract

Nitric oxide (NO) inhibits collecting duct (CD) Na

Indexed as

AnimalsBlood PressureDrinkingEatingFemaleKidneyKidney Tubules, CollectingMaleMiceMice, KnockoutNitric Oxide Synthase Type IIIOsmolar ConcentrationReninSex FactorsWaterNitric Oxide Synthase Type IIINos3 protein, mouseReninWatercollecting ductgenderknockoutnitric oxide synthaseurinary water excretion

Identifiers

PMID27707708
PMCPMC5130459
OpenAlexW2528310286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.