Evidence map›Paper›PMID 27707705›Full record

ArticleAmerican journal of physiology. Renal physiology2016

A computational model for simulating solute transport and oxygen consumption along the nephrons.

Anita T Layton, Volker Vallon, Aurélie Edwards

Abstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 85 citations in OpenAlex.

  1. Article
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  10. Sex differences in circadian regulation of kidney function of the mouse.American journal of physiology. Renal physiology · 2022
    Article
  11. Article
  12. Article
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  14. A mathematical model of the rat kidney. III. Ammonia transport.American journal of physiology. Renal physiology · 2021
    Article
  15. A Computational Model of Kidney Function in a Patient with Diabetes.International journal of molecular sciences · 2021
    Review
  16. Article
  17. Article
  18. Review
  19. Sex-specific computational models for blood pressure regulation in the rat.American journal of physiology. Renal physiology · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Anita T LaytonDepartment of Mathematics, Duke University, Durham, North Carolina; alayton@math.duke.edu.
Volker VallonDepartments of Medicine and Pharmacology, University of California San Diego, La Jolla, California, and San Diego Veterans Affairs Healthcare System, San Diego, California.
Aurélie EdwardsSorbonne Universités, UPMC Univ Paris 06, Université Paris Descartes, Sorbonne Paris Cité, INSERM UMRS 1138, CNRS ERL 8228, Centre de Recherche des Cordeliers, Paris, France; and.
Duke University · USUniversité Paris Cité · FRVA San Diego Healthcare System · US

Funding

UAB-UCSD O'Brien Core Center for Acute Kidney Injury ResearchP30DK079337 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI AGARWAL, ANUPAM · 2008 to 2022
$18.3M
GLOMERULAR AND TUBULAR FUNCTION IN THE DIABETIC KIDNEYR01DK056248 · NIDDK · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI THOMSON, SCOTT CULVER · 1999 to 2014
$4.6M
Unraveling Kidney Physiology, Pathophysiology & Therapeutics: A Modeling ApproachR01DK106102 · NIDDK · DUKE UNIVERSITY · PI LAYTON, ANITA · 2016 to 2019
$1.4M
Modeling Solute Transport and Urine Concentrating Mechanism in the Rat KidneyR01DK089066 · NIDDK · DUKE UNIVERSITY · PI LAYTON, ANITA · 2010 to 2014
$1.2M
NIDDK NIH HHS P30 DK079337NIDDK NIH HHS R01 DK056248NIDDK NIH HHS R01 DK089066NIDDK NIH HHS R01 DK106102
6 · The paper itself

Abstract

The goal of this study was to investigate water and solute transport, with a focus on sodium transport (T

Indexed as

Models, BiologicalAnimalsBiological TransportComputer SimulationKidneyNephronsOxygen ConsumptionRatsepithelial transportmetabolismoxygen consumptionsodium transport

Identifiers

PMID27707705
PMCPMC5210192
OpenAlexW2527990943

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.