Trial reportJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2017
Vitamin D Improves Selected Metabolic Parameters but Not Neuropsychological or Quality of Life Indices in OSA: A Pilot Study.
Trial report in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Obstructive sleep apnea and vitamin D: an updated systematic review and meta-analysis.Hormones (Athens, Greece) · 2023Pooled it
- Vitamin D Supplementation and Sleep: A Systematic Review and Meta-Analysis of Intervention Studies.Nutrients · 2022Pooled it
- The association between serum vitamin D and obstructive sleep apnea: an updated meta-analysis.Respiratory research · 2020Pooled it
- A systematic review and meta-analysis of the response of serum 25-hydroxyvitamin D concentration to vitamin D supplementation from RCTs from around the globe.European journal of clinical nutrition · 2019Pooled it
- Unveiling the benefits of Vitamin D3 with SGLT-2 inhibitors for hypertensive obese obstructive sleep apnea patients.Journal of translational medicine · 2025Trial
- Effect of omega-3 and vitamin D co-supplementation on psychological distress in reproductive-aged women with pre-diabetes and hypovitaminosis D: A randomized controlled trial.Brain and behavior · 2021Trial
- Vitamin D and Sleep Disorders.Advances in experimental medicine and biology · 2026Review
- A Prospective Observational Study Investigating the Relationship Between Vitamin D Deficiency and STOP-Bang Parameters in Elderly Populations.Nature and science of sleep · 2025Article
- Obstructive sleep apnea and vitamin D level: Has the dust settled?The clinical respiratory journal · 2024Review
- Associations between serum vitamin D status and the cardiometabolic profile of patients with obstructive sleep apnea.Hormones (Athens, Greece) · 2023Article
- Article
- Review
- Article
- Sleep duration is associated with vitamin D deficiency in older women living in Macao, China: A pilot cross-sectional study.PloS one · 2020Article
- The role of vitamin D in obstructive sleep apnoea syndrome.Breathe (Sheffield, England) · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesOur group and others have reported a high rate of vitamin D deficiency in obstructive sleep apnea (OSA), where vitamin D levels (25(OH) D) correlate negatively with OSA severity and some of its associated metabolic alterations. Data regarding vitamin D supplementation in OSA are lacking. We wanted to evaluate the effect of vitamin D
methodsWe conducted a pilot, double-blind, randomized, placebo-controlled trial of daily supplementation with 4,000 IU vitamin D
resultsThere was no change in BMI, medication, or CPAP usage. Although there was no change in neuropsychological or quality of life indices, we observed a significant increase in 25(OH)D (p = 0.00001) and significant decreases in both low-density lipoprotein (p = 0.04) and lipoprotein-associated phospholipase A2 (p = 0.037) as well as trends toward decreased fasting glucose (p = 0.09) and increased high-density lipoprotein (p = 0.07) in the D
conclusionsVitamin D
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.