ArticlePLoS neglected tropical diseases2016
Retrospective Analysis of Serotype Switching of Vibrio cholerae O1 in a Cholera Endemic Region Shows It Is a Non-random Process.
Article in PLoS neglected tropical diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Vibrio cholerae serotype impacts pathogenicity.Nature communications · 2026Article
- Article
- Gut bacteria-derived sphingolipids alter innate immune responses to oral cholera vaccine antigens.Nature communications · 2025Article
- Genomic characterization of multidrug-resistant extended-spectrum β-lactamase-producing Vibrio cholerae O1 strains from 2022 cholera outbreak in Kenya.The Journal of antimicrobial chemotherapy · 2025Article
- Recent and convergent reversion to serotype Ogawa in the AFR12 sublineage ofMicrobial genomics · 2025Article
- Rapid tests as a practical alternative to slide agglutination for the confirmation ofJournal of clinical microbiology · 2025Article
- Epidemiologic and Genomic Surveillance of Vibrio cholerae and Effectiveness of Single-Dose Oral Cholera Vaccine, Democratic Republic of the Congo.Emerging infectious diseases · 2025Article
- Effectiveness of a single dose of oral cholera vaccine: findings from epidemiological and genomic surveillance ofmedRxiv : the preprint server for health sciences · 2024Article
- Vibrio cholerae O1 associated with recent endemic cholera shows temporal changes in serotype, genotype, and drug-resistance patterns in Bangladesh.Gut pathogens · 2023Article
- Molecular Basis of the Toxigenic Vibrio cholerae O1 Serotype Switch from Ogawa to Inaba in Haiti.Microbiology spectrum · 2023Article
- Serotype conversion geneFrontiers in microbiology · 2023Article
- Article
- Article
- Dissecting serotype-specific contributions to live oral cholera vaccine efficacy.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Genomics of the Argentinian cholera epidemic elucidate the contrasting dynamics of epidemic and endemic Vibrio cholerae.Nature communications · 2020Article
- Article
- Review
- Revisiting the Global Epidemiology of Cholera in Conjuction With the Genomics ofFrontiers in public health · 2019Review
- Cholera: Immunity and Prospects in Vaccine Development.The Journal of infectious diseases · 2018Article
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Authors and funding
10 authors.
Funding
Abstract
Genomic data generated from clinical Vibrio cholerae O1 isolates collected over a five year period in an area of Kolkata, India with seasonal cholera outbreaks allowed a detailed genetic analysis of serotype switching that occurred from Ogawa to Inaba and back to Ogawa. The change from Ogawa to Inaba resulted from mutational disruption of the methyltransferase encoded by the wbeT gene. Re-emergence of the Ogawa serotype was found to result either from expansion of an already existing Ogawa clade or reversion of the mutation in an Inaba clade. Our data suggests that such transitions are not random events but rather driven by as yet unidentified selection mechanisms based on differences in the structure of the O1 antigen or in the serotype-determining wbeT gene.
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