Evidence map›Paper›PMID 27706097›Full record

ArticleMolecules (Basel, Switzerland)2016

Anti-Inflammatory Effects of Aspalathus linearis and Cyclopia spp. Extracts in a UVB/Keratinocyte (HaCaT) Model Utilising Interleukin-1α Accumulation as Biomarker.

Tandeka Magcwebeba, Pieter Swart, Sonja Swanevelder, Elizabeth Joubert, Wentzel Gelderblom

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 49 citations in OpenAlex.

  1. Properties of Aspalathus linearis extracts as sunscreen agents in combination with standard UV filters.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  2. From Reshaped Metabolome to Repaired Skin: FermentedAntioxidants (Basel, Switzerland) · 2025
    Article
  3. Magnolin Mitigates Skin Ageing Through the CXCL10/p38 Signalling Pathway.Journal of cellular and molecular medicine · 2025
    Article
  4. Exploring the In Vitro Photoprotective Effect of a Combination ofInternational journal of molecular sciences · 2025
    Article
  5. The effect ofFrontiers in physiology · 2023
    Article
  6. Skin Aging, Cellular Senescence and Natural Polyphenols.International journal of molecular sciences · 2021
    Review
  7. Article
  8. Therapeutic Effects ofAntioxidants (Basel, Switzerland) · 2021
    Article
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  13. Review
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  15. Review
  16. Natural Products and Inflammation.Molecules (Basel, Switzerland) · 2017
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Tandeka MagcwebebaDepartment of Biochemistry, Stellenbosch University, Private Bag X1, Matieland (Stellenbosch) 7602, South Africa. tmagcwebeba@sun.ac.za.
Pieter SwartDepartment of Biochemistry, Stellenbosch University, Private Bag X1, Matieland (Stellenbosch) 7602, South Africa. pswart@sun.ac.za.
Sonja SwanevelderBiostatistics Unit, South African Medical Research Council, P.O. Box 19070, Tygerberg 7505, South Africa. sonja.swanevelder@mrc.ac.za.
Elizabeth JoubertPost-Harvest and Wine Technology Division, Agricultural Research Council (Infruitec-Nietvoorbij), Private Bag X5026, Stellenbosch 7599, South Africa. joubertL@arc.agric.za.
Wentzel GelderblomDepartment of Biochemistry, Stellenbosch University, Private Bag X1, Matieland (Stellenbosch) 7602, South Africa. gelderblomw@cput.ac.za.
Stellenbosch University · ZACape Peninsula University of Technology · ZASouth African Medical Research Council · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultraviolet B (UVB) radiation is one of the major predisposing risk factors of skin cancer. The anticancer and photoprotective effects of unoxidized rooibos (

Indexed as

Anti-Inflammatory AgentsAspalathusBiomarkersCell LineCell ProliferationCell SurvivalCyclopia PlantFabaceaeGene Expression RegulationHumansInterleukin-1alphaKeratinocytesModels, BiologicalPlant ExtractsTeaTeas, HerbalAnti-Inflammatory AgentsBiomarkersIL1A protein, humanInterleukin-1alphaPlant ExtractsTeaTeas, Herbalanti-inflammatory effectsantioxidantsdihydrochalconesflavanonesherbal tea polyphenolsUVB irradiationxanthones

Identifiers

PMID27706097
PMCPMC6274390
OpenAlexW2529681420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.