Evidence map›Paper›PMID 27706066›Full record

ArticleInternational journal of environmental research and public health2016

Effects of Short-Term Exposure to Particulate Air Pollutants on the Inflammatory Response and Respiratory Symptoms: A Panel Study in Schoolchildren from Rural Areas of Japan.

Masanari Watanabe, Hisashi Noma, Jun Kurai, Hiroyuki Sano, Degejirihu Hantan, Masaru Ueki, Hiroya Kitano, Eiji Shimizu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Ozone augments interleukin-8 production induced by ambient particulate matter.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2018
    Article
  5. Fine Particulate Matter in Urban Environments: A Trigger of Respiratory Symptoms in Sensitive Children.International journal of environmental research and public health · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Masanari WatanabeDepartment of Respiratory Medicine and Rheumatology, Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonago 683-8504, Japan. watanabm@grape.med.tottori-u.ac.jp.
Hisashi NomaDepartment of Data Science, Institute of Statistical Mathematics, 10-3 Midori-cho, Tachikawa, Tokyo 190-8562, Japan. noma@ism.ac.jp.
Jun KuraiDepartment of Respiratory Medicine and Rheumatology, Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonago 683-8504, Japan. junkurajun@gmail.com.
Hiroyuki SanoDepartment of Respiratory Medicine and Allergology, Faculty of Medicine, Kinki University, Ohnohigashi 377-2, Osakasayama 589-0014, Japan. hsano@med.kindai.ac.jp.
Degejirihu HantanDepartment of Respiratory Medicine and Rheumatology, Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonago 683-8504, Japan. degujirefu@med.tottori-u.ac.jp.
Masaru UekiCenter for Promoting Next-Generation Highly Advanced Medicine, Tottori University Hospital, 36-1 Nishi-cho, Yonago 683-8504, Japan. masaruueki@gmail.com.
Hiroya KitanoThe Board of Directors, Tottori University, 36-1 Nishi-cho, Yonago 683-8504, Japan. hkitano@med.tottori-u.ac.jp.
Eiji ShimizuDepartment of Respiratory Medicine and Rheumatology, Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonago 683-8504, Japan. eiji@med.tottori-u.ac.jp.
Tottori University · JPKindai University · JPThe Institute of Statistical Mathematics · JPTottori University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relationship between particulate air pollutants and respiratory symptoms in children has not been consistent among studies, potentially owing to differences in the inflammatory response to different particulate air pollutants. This study aimed to investigate the effect of particulate air pollutants on respiratory symptoms and the inflammatory response in schoolchildren. Three hundred-and-sixty children were included in the study. The children recorded daily respiratory symptom scores for October 2015. In addition, the daily amount of interleukin (IL)-6, IL-8, and tumor necrosis factor (TNF)-α production was assessed in THP1 cells stimulated with suspended particulate matter (SPM), which was collected every day during the study period. Generalized estimating equation logistic regression analyses were used to estimate the associations among respiratory symptoms and the daily levels of SPM, IL-6, IL-8, and TNF-α. Daily SPM levels were not associated with respiratory symptoms or the daily IL-6, IL-8, and TNF-α levels. Conversely, there was a significant association between respiratory symptoms and the daily IL-6, IL-8, and TNF-α levels. These results suggested that the effects of particulate air pollutants on respiratory symptoms in schoolchildren might depend more on the pro-inflammatory response to them than on their mass concentration.

Indexed as

AdolescentAir PollutantsChildFemaleHumansInflammationInterleukin-6Interleukin-8JapanMaleParticulate MatterRespiratory Tract DiseasesTime FactorsTumor Necrosis Factor-alphaAir PollutantsCXCL8 protein, humanIL6 protein, humanInterleukin-6Interleukin-8Particulate MatterTumor Necrosis Factor-alphaparticulate air pollutantspro-inflammatory cytokinerespiratory symptomschoolchildren

Identifiers

PMID27706066
PMCPMC5086722
OpenAlexW2525988510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.