Evidence map›Paper›PMID 27706020›Full record

ReviewAntioxidants (Basel, Switzerland)2016

Berry Fruit Consumption and Metabolic Syndrome.

Stefano Vendrame, Cristian Del Bo', Salvatore Ciappellano, Patrizia Riso, Dorothy Klimis-Zacas

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 4 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 4 syntheses or guidelines pooled it, 110 citations in OpenAlex.

  1. Pooled it
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  4. Impact of Obesity-Induced Inflammation on Cardiovascular Diseases (CVD).International journal of molecular sciences · 2021
    Pooled it
  5. Trial
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  8. Review
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  10. Alaska's Flora as a Treatment for Cancer.International journal of biopharmaceutical sciences · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Stefano VendrameSchool of Food and Agriculture, Food Science and Human Nutrition, University of Maine, Orono, ME 04469, USA. stefano.vendrame@fulbrightmail.org.
Cristian Del Bo'DeFENS-Department of Food, Environmental and Nutritional Sciences, Division of Human Nutrition, Università degli Studi di Milano, 20133 Milan, Italy. cristian.delbo@unimi.it.
Salvatore CiappellanoDeFENS-Department of Food, Environmental and Nutritional Sciences, Division of Human Nutrition, Università degli Studi di Milano, 20133 Milan, Italy. salvatore.ciappellano@unimi.it.
Patrizia RisoDeFENS-Department of Food, Environmental and Nutritional Sciences, Division of Human Nutrition, Università degli Studi di Milano, 20133 Milan, Italy. patrizia.riso@unimi.it.
Dorothy Klimis-ZacasSchool of Food and Agriculture, Food Science and Human Nutrition, University of Maine, Orono, ME 04469, USA. Dorothy_Klimis_Zacas@umit.maine.edu.
University of Milan · ITUniversity of Maine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic Syndrome is a cluster of risk factors which often includes central obesity, dyslipidemia, insulin resistance, glucose intolerance, hypertension, endothelial dysfunction, as well as a pro-inflammatory, pro-oxidant, and pro-thrombotic environment. This leads to a dramatically increased risk of developing type II diabetes mellitus and cardiovascular disease, which is the leading cause of death both in the United States and worldwide. Increasing evidence suggests that berry fruit consumption has a significant potential in the prevention and treatment of most risk factors associated with Metabolic Syndrome and its cardiovascular complications in the human population. This is likely due to the presence of polyphenols with known antioxidant and anti-inflammatory effects, such as anthocyanins and/or phenolic acids. The present review summarizes the findings of recent dietary interventions with berry fruits on human subjects with or at risk of Metabolic Syndrome. It also discusses the potential role of berries as part of a dietary strategy which could greatly reduce the need for pharmacotherapy, associated with potentially deleterious side effects and constituting a considerable financial burden.

Indexed as

berriesdietary intervention studieshumansMetabolic Syndrome

Identifiers

PMID27706020
PMCPMC5187532
OpenAlexW2525044508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.