Evidence map›Paper›PMID 27705955›Full record

ArticleJournal of neural engineering2016

Changing head model extent affects finite element predictions of transcranial direct current stimulation distributions.

Aprinda Indahlastari, Munish Chauhan, Benjamin Schwartz, Rosalind J Sadleir

Abstract read
In one paragraph

Article in Journal of neural engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Modeling for Electromagnetic Characterization, Prediction, and Reconstruction.Advances in experimental medicine and biology · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aprinda IndahlastariSchool of Biological and Health Systems Engineering, Arizona State University, Box 879709, Tempe AZ, USA.
Munish ChauhanSchool of Biological and Health Systems Engineering, Arizona State University, Box 879709, Tempe AZ, USA.
Benjamin SchwartzSchool of Biological and Health Systems Engineering, Arizona State University, Box 879709, Tempe AZ, USA.
Rosalind J SadleirSchool of Biological and Health Systems Engineering, Arizona State University, Box 879709, Tempe AZ, USA.

Funding

In vivo imaging of therapeutic electric current flowR21NS081646 · NINDS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI SADLEIR, ROSALIND J · 2014 to 2015
$410k
NINDS NIH HHS R21 NS081646
6 · The paper itself

Abstract

objectiveIn this study, we determined efficient head model sizes relative to predicted current densities in transcranial direct current stimulation (tDCS). APPROACH: Efficiency measures were defined based on a finite element (FE) simulations performed using nine human head models derived from a single MRI data set, having extents varying from 60%-100% of the original axial range. Eleven tissue types, including anisotropic white matter, and three electrode montages (T7-T8, F3-right supraorbital, Cz-Oz) were used in the models. MAIN

resultsReducing head volume extent from 100% to 60%, that is, varying the model's axial range from between the apex and C3 vertebra to one encompassing only apex to the superior cerebellum, was found to decrease the total modeling time by up to half. Differences between current density predictions in each model were quantified by using a relative difference measure (RDM). Our simulation results showed that [Formula: see text] was the least affected (a maximum of 10% error) for head volumes modeled from the apex to the base of the skull (60%-75% volume). SIGNIFICANCE: This finding suggested that the bone could act as a bioelectricity boundary and thus performing FE simulations of tDCS on the human head with models extending beyond the inferior skull may not be necessary in most cases to obtain reasonable precision in current density results.

Indexed as

Models, AnatomicAlgorithmsAnisotropyBone and BonesCerebellumElectric ConductivityElectrodesFinite Element AnalysisForecastingGray MatterHeadHumansMagnetic Resonance ImagingSkullTranscranial Direct Current StimulationWhite Matter

Identifiers

PMID27705955
PMCPMC5361410

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.