Evidence map›Paper›PMID 27705926›Full record

ArticleAging2016

Caveolin-1 controls mitochondrial function through regulation of

Daniela Volonte, Zhongmin Liu, Sruti Shiva, Ferruccio Galbiati

Open access · greenAbstract read
In one paragraph

Article in Aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Breath of Fresh Air: Toward Unraveling the Molecular Underpinnings of Sleep Apnea.American journal of respiratory and critical care medicine · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Caveolins as Regulators of Stress Adaptation.Molecular pharmacology · 2018
    Review
  15. Article
  16. Caveolin-1: An Oxidative Stress-Related Target for Cancer Prevention.Oxidative medicine and cellular longevity · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Daniela VolonteDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
Zhongmin LiuDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
Sruti ShivaDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
Ferruccio GalbiatiDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
University of Pittsburgh · US

Funding

Caveolin 1: a novel modulator of the PP2A/ATM/p53 pathwayR01AG030636 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GALBIATI, FERRUCCIO · 2009 to 2013
$1.5M
Caveolin-1-mediated senescence, chronic inflammation and age-related lung diseaseR01HL124747 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GALBIATI, FERRUCCIO · 2015 to 2017
$1.2M
NHLBI NIH HHS R01 HL124747NIA NIH HHS R01 AG030636
6 · The paper itself

Abstract

Mitochondrial proteases ensure mitochondrial integrity and function after oxidative stress by providing mitochondrial protein quality control. However, the molecular mechanisms that regulate this basic biological function in eukaryotic cells remain largely unknown. Caveolin-1 is a scaffolding protein involved in signal transduction. We find that AFG3L2, a

Indexed as

AnimalsCaveolin 1Cells, CulturedElectron Transport Complex IFibroblastsHydrogen PeroxideMetalloendopeptidasesMiceMice, KnockoutMitochondriaOxidative StressCaveolin 1Electron Transport Complex IHydrogen Peroxidem-AAA proteasesMetalloendopeptidasescaveolaecaveolin-1glycolysismitochondriaoxidative stress

Identifiers

PMID27705926
PMCPMC5115893
OpenAlexW2530552047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.