Evidence map›Paper›PMID 27704468›Full record

ReviewCurrent hematologic malignancy reports2016

Sézary Syndrome: Clinical and Biological Aspects.

Rebecca Kohnken, Stephanie Fabbro, Justin Hastings, Pierluigi Porcu, Anjali Mishra

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current hematologic malignancy reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Types of T-cell lymphoma-a cytogenetic perspective.Annals of medicine and surgery (2012) · 2022
    Article
  3. The Role of Tumor Microenvironment in the Pathogenesis of Sézary Syndrome.International journal of molecular sciences · 2022
    Review
  4. Article
  5. Article
  6. Article
  7. Multidisciplinary Management of Mycosis Fungoides/Sézary Syndrome.Current hematologic malignancy reports · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rebecca KohnkenDepartment of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, USA.
Stephanie FabbroDivision of Dermatology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
Justin HastingsDivision of Dermatology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA.
Pierluigi PorcuComprehensive Cancer Center, James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, OH, USA. pierluigi.Porcu@osumc.edu.
Anjali MishraDivision of Dermatology, Department of Internal Medicine, The Ohio State University, Columbus, OH, USA. anjali.mishra@osumc.edu.
The Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sézary syndrome (SS) is a rare and aggressive type of cutaneous T cell lymphoma (CTCL) characterized by an intensely pruritic, exfoliative rash, known as erythroderma, with cutaneous and systemic dissemination of clonal CD4+ T cells into the blood and lymph nodes. This review aims to present recent advancements in the biological and clinical aspects of SS. We begin by providing an overview of the diagnostic criteria for SS and reviewing some of its epidemiological and clinical aspects. We then discuss updates in the etiology of this elusive disease and the genetic and molecular landscapes that define it. Finally, we provide a short overview of the current therapeutic strategies for SS as well as recent advances in the prognosis of this disease. A brief set of recommendations is provided regarding future directions in research and therapy.

Indexed as

CD4-Positive T-LymphocytesEnzyme InhibitorsEpigenomicsHumansImmunologic FactorsLymphoma, T-Cell, CutaneousNeoplasm StagingSezary SyndromeSignal TransductionEnzyme InhibitorsImmunologic FactorsCutaneous T cell lymphomaLymphoproliferative malignanciesSézary syndrome

Identifiers

PMID27704468
OpenAlexW2527945862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.