Evidence map›Paper›PMID 27704308›Full record

ArticleEnvironmental geochemistry and health2017

Toxicants in folk remedies: implications of elevated blood lead in an American-born infant due to imported diaper powder.

Mateusz P Karwowski, Suzette A Morman, Geoffrey S Plumlee, Terence Law, Mark Kellogg, Alan D Woolf

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Environmental geochemistry and health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mateusz P KarwowskiDepartment of Medicine, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, USA. matt.karwowski@childrens.harvard.edu.
Suzette A MormanU. S. Geological Survey, Denver, CO, USA.
Geoffrey S PlumleeU. S. Geological Survey, Denver, CO, USA.
Terence LawDepartment of Laboratory Medicine, Boston Children's Hospital, Boston, MA, USA.
Mark KelloggDepartment of Laboratory Medicine, Boston Children's Hospital, Boston, MA, USA.
Alan D WoolfDepartment of Medicine, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, USA.
Boston Children's Hospital · USUnited States Geological Survey · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Though most childhood lead exposure in the USA results from ingestion of lead-based paint dust, non-paint sources are increasingly implicated. We present interdisciplinary findings from and policy implications of a case of elevated blood lead (13-18 mcg/dL, reference level <5 mcg/dL) in a 9-month-old infant, linked to a non-commercial Malaysian folk diaper powder. Analyses showed the powder contains 62 % lead by weight (primarily lead oxide) and elevated antimony [1000 parts per million (ppm)], arsenic (55 ppm), bismuth (110 ppm), and thallium (31 ppm). These metals are highly bioaccessible in simulated gastric fluids, but only slightly bioaccessible in simulated lung fluids and simulated urine, suggesting that the primary lead exposure routes were ingestion via hand-mouth transmission and ingestion of inhaled dusts cleared from the respiratory tract. Four weeks after discontinuing use of the powder, the infant's venous blood lead level was 8 mcg/dL. Unregulated, imported folk remedies can be a source of toxicant exposure. Additional research on import policy, product regulation, public health surveillance, and culturally sensitive risk communication is needed to develop efficacious risk reduction strategies in the USA. The more widespread use of contaminated folk remedies in the countries from which they originate is a substantial concern.

Indexed as

Diapers, InfantEnvironmental ExposureBostonFemaleHazardous SubstancesHumansInfantLeadMalaysiaMedicine, TraditionalOxidesPowdersHazardous SubstancesLeadlead oxideOxidesPowdersBaby powderChildhood lead poisoningFolk remediesLead contaminationMetals toxicityRegulatory policy

Identifiers

PMID27704308
OpenAlexW2527735273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.