Trial reportLasers in medical science2017
Photodynamic therapy decrease immune-inflammatory mediators levels during periodontal maintenance.
Trial report in Lasers in medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 6 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Clinical effect of immunomodulatory therapy in periodontitis: a systematic review and meta-analysis.Frontiers in bioengineering and biotechnology · 2025Pooled it
- Gingival crevicular fluid level of tumor necrosis factor-alpha as a valuable biomarker for estimation of the efficacy of adjunctive antimicrobial photodynamic therapy in stage II-IV periodontitis: a systematic review and meta-analysis.Lasers in medical science · 2024Pooled it
- Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri-implant diseases.The Cochrane database of systematic reviews · 2024Pooled it
- The Efficacy of Adjunctive Aids in Periodontal Maintenance Therapy: A Systematic Literature Review and Meta-analysis.Oral health & preventive dentistry · 2020Pooled it
- The effects of repeated applications of antimicrobial photodynamic therapy in the treatment of residual periodontal pockets: a systematic review.Lasers in medical science · 2019Pooled it
- Supportive periodontal therapy (SPT) for maintaining the dentition in adults treated for periodontitis.The Cochrane database of systematic reviews · 2018Pooled it
- Comparison of antimicrobial photodynamic therapy protocols as adjunct treatment in the management of initial pericoronitis: a randomized, controlled, double-blind clinical trial.Clinical oral investigations · 2026Trial
- Adjuvant antimicrobial photodynamic therapy improves periodontal health and reduces inflammatory cytokines in patients with type 1 diabetes mellitus.Journal of applied oral science : revista FOB · 2024Trial
- Antimicrobial photodynamic therapy protocol for dental implant surfaces decontamination in vitro: A comparison between methylene blue and toluidine blue O.Lasers in medical science · 2025Article
- Blue Photosensitizer, Red Light, Clear Results: An Integrative Review of the Adjunctive Periodontal Treatment with Methylene Blue in Antimicrobial Photodynamic Therapy.Dentistry journal · 2025Review
- Effects of Antimicrobial Photosensitizers of Photodynamic Therapy (PDT) to Treat Periodontitis.Current pharmaceutical biotechnology · 2024Review
- Application of Different Wavelengths of LED Lights in Antimicrobial Photodynamic Therapy for the Treatment of Periodontal Disease.Antibiotics (Basel, Switzerland) · 2023Review
- Clinical applications of antimicrobial photodynamic therapy in dentistry.Frontiers in microbiology · 2022Review
- Laser-Assisted aPDT Protocols in Randomized Controlled Clinical Trials in Dentistry: A Systematic Review.Dentistry journal · 2020Review
- Cytokine levels in crevicular fluid associated with compliance during periodontal maintenance therapy.Clinical oral investigations · 2019Article
- Effect of one and two sessions of antimicrobial photodynamic therapy on clinical and microbial outcomes of non-surgical management of chronic periodontitis: A clinical study.Journal of advanced periodontology & implant dentistry · 2019Article
- Levels of Pro and Anti-inflammatory Citokynes and C-Reactive Protein in Patients with Chronic Periodontitis Submitted to Nonsurgical Periodontal TreatmentAsian Pacific journal of cancer prevention : APJCP · 2018Article
- Effect of adjunctive photodynamic therapy on gingival crevicular fluid interleukin-1β in Stage III and IV periodontitis: A systematic review and meta-analysis.Journal of Indian Society of PeriodontologyReview
- Effect of non-surgical periodontal therapy on the serum and crevicular fluid interleukin-10 levels in chronic periodontitis - A systematic review and meta-analysis.International journal of health sciencesReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antimicrobial photodynamic therapy (aPDT) was introduced as a promising adjuvant therapy on the periodontal treatment. The aim of this study was to evaluate the effect of aPDT on inflammatory mediator levels in residual periodontal pockets of patients with severe chronic periodontitis under periodontal maintenance, during 12 months follow-up. A randomized controlled trial study was conducted in 28 patients with severe chronic periodontitis. After non-surgical periodontal treatment, patients with at least four teeth with residual pocket probing depth (PPD) ≥4 mm were randomly assigned to either aPDT or control group. The aPDT (low power laser: 660 nm, 40 mW, 90 J/cm
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.