Evidence map›Paper›PMID 27704222›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2016

Distinct differences in metal ion specificity of RNA and DNA G-quadruplexes.

Helena Guiset Miserachs, Daniela Donghi, Richard Börner, Silke Johannsen, Roland K O Sigel

Abstract read
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In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 59 citations in OpenAlex.

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  9. Sequence and ionic requirements of pUG fold quadruplexes.bioRxiv : the preprint server for biology · 2025
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  17. Quantum tunneling time delay investigation ofJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Helena Guiset MiserachsDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
Daniela DonghiDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland.
Richard BörnerDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland. richard.boerner@chem.uzh.ch.
Silke JohannsenDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland. silke.johannsen@chem.uzh.ch.
Roland K O SigelDepartment of Chemistry, University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland. roland.sigel@chem.uzh.ch.
University of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA G-quadruplexes, as their well-studied DNA analogs, require the presence of cations to fold and remain stable. This is the first comprehensive study on the interaction of RNA quadruplexes with metal ions. We investigated the formation and stability of two highly conserved and biologically relevant RNA quadruplex-forming sequences (24nt-TERRA and 18nt-NRAS) in the presence of several monovalent and divalent metal ions, namely Li

Indexed as

G-QuadruplexesBase SequenceCations, DivalentCations, MonovalentCircular DichroismDNAHydrogen-Ion ConcentrationMetalsNucleic Acid DenaturationOligonucleotidesRNASpectrophotometryTemperatureThermodynamicsWaterCations, DivalentCations, MonovalentDNAMetalsOligonucleotidesRNAWaterCircular dichroismMetal ionsNRAS/TERRARNA G-quadruplexesUV thermal melting

Identifiers

PMID27704222
OpenAlexW2528870882

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.