ArticleRheumatology international2017
Relationship between cigarette smoking and hyperuricemia in middle-aged and elderly population: a cross-sectional study.
Article in Rheumatology international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Association between periodontitis and uric acid levels in blood and oral fluids: a systematic review and meta-analysis.BMC oral health · 2023Pooled it
- Demographic, regional and temporal trends of hyperuricemia epidemics in mainland China from 2000 to 2019: a systematic review and meta-analysis.Global health action · 2021Pooled it
- Preliminary analysis of lifestyle and genetic factors for hyperuricemia and gout prevalence in the Yunnan Miao population of China.Frontiers in genetics · 2026Article
- Association between secondhand smoke exposure and hyperuricemia among never smokers: A cross-sectional analysis of NHANES data.Tobacco induced diseases · 2026Article
- Association of uric acid to high-density cholesterol ratio (UHR) with biological age acceleration: evidence from NHANES 2009-2018.Scientific reports · 2025Article
- Effects of thyroid-stimulating hormone and sensitivity to thyroid hormones on the risk of hyperuricemia in euthyroid adults.Archives of endocrinology and metabolism · 2025Observational
- Inverse relationship of oxidative balance score with hyperuricemia among Chinese adults: a population-based cross-sectional study.BMC public health · 2025Observational
- Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and hyperuricemia: evidence from the CHARLS study.Frontiers in nutrition · 2025Article
- The association between smoking and the occurrence of hyperuricemia: A retrospective cohort study.Tobacco induced diseases · 2025Article
- One-Year Risk Prediction of Elevated Serum Uric Acid Levels in Older Adults: A Longitudinal Cohort Study.Clinical interventions in aging · 2024Article
- Associations of oxidative balance score with hyperuricemia and gout among American adults: a population-based study.Frontiers in endocrinology · 2024Article
- Women with Metabolic Syndrome and Unhealthy Lifestyle Factors Are at a Higher Risk for Hyperuricemia.Journal of clinical medicine · 2023Article
- Interaction of Harmful Alcohol Use and Tea Consumption on Hyperuricemia Among Han Residents Aged 30-79 in Chongqing, China.International journal of general medicine · 2023Article
- Monocyte to high-density lipoprotein cholesterol ratio and serum uric acid in Chinese adults: a cross-sectional study.BMC endocrine disorders · 2022Article
- Prevalence of hyperuricemia and the population attributable fraction of modifiable risk factors: Evidence from a general population cohort in China.Frontiers in public health · 2022Article
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- Association of urinary cotinine-verified smoking status with hyperuricemia: Analysis of population-based nationally representative data.Tobacco induced diseases · 2020Article
- Risk Factors For Hyperuricemia In Chinese Centenarians And Near-Centenarians.Clinical interventions in aging · 2019Article
- Markers of Iron Status Are Associated with Risk of Hyperuricemia among Chinese Adults: Nationwide Population-Based Study.Nutrients · 2018Observational
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to estimate the cross-sectional association between cigarette smoking and the prevalence of hyperuricemia (HU) in the middle-aged and elderly males and females. A total of 3415 males and 2932 females were included in this study. HU was defined as SUA≥ 416 mmol/L for males and ≥360 mmol/L for females. The smoking status was classified into four categories based on daily smoking habit: (1) 0/day; (2) 1-10/day; (3) 11-20/day; and (4) >20/day. Multivariable logistic regressions were conducted to examine the aforementioned association. The prevalence of HU in the male and female sample was 25.0 and 10.0 %, respectively. In male subjects, the prevalence of HU in smokers (22.8 %) was significantly lower than that in non-smokers (26.5 %) (p = 0.016). Meanwhile, with adjustment for potential confounding factors, the prevalence of HU in smokers was still lower (OR = 0.83, 95 % CI 0.70-0.98, P = 0.033). Furthermore, a significantly inverse association between smoking status and HU was observed in the multivariable model. The multivariable-adjusted OR (95 % CI) for HU in the second, third and fourth category of smoking status was 0.84 (95 % CI 0.66-1.06), 0.90 (95 % CI 0.69-1.18) and 0.76 (95 % CI 0.58-0.99), respectively, compared with that in the first category. A clear trend (P for trend was 0.036) was observed. However, there was no significant association between cigarette smoking and HU in female subjects (P for trend was 0.739). This study indicated an inverse association between cigarette smoking and the prevalence of HU in the middle-aged and elderly male population, independent of some major confounding factors. The findings of this study expect further prospective studies to confirm the causal relationship.
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