Evidence map›Paper›PMID 27704139›Full record

ArticleMolecular medicine (Cambridge, Mass.)2016

Pigmy MicroRNA: surveillance cops in Therapies kingdom.

Utpal Bhadra, Pradipta Patra, Jagamohan Chhatai, Manika Pal-Bhadra

Open access · goldAbstract read
In one paragraph

Article in Molecular medicine (Cambridge, Mass.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Utpal BhadraFunctional Genomics and Gene Silencing Group, Centre for Cellular and Molecular Biology (CSIR-CCMB), Uppal Road, Hyderabad - 500 007, India.
Pradipta PatraFunctional Genomics and Gene Silencing Group, Centre for Cellular and Molecular Biology (CSIR-CCMB), Uppal Road, Hyderabad - 500 007, India.
Jagamohan ChhataiFunctional Genomics and Gene Silencing Group, Centre for Cellular and Molecular Biology (CSIR-CCMB), Uppal Road, Hyderabad - 500 007, India.
Manika Pal-BhadraCentre for Chemical Biology, Indian Institute of Chemical Technology (CSIR-IICT), Uppal Road, Hyderabad-500 007, India.
Centre for Cellular and Molecular Biology · INIndian Institute of Chemical Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are well preserved in every animal. These pigmy sized non-coding RNAs (21-23 nt), scattered in genome, are responsible for micromanaging the versatile gene regulations. Involvement of miRNAs was surveillance cops in all human diseases including cardiovascular defects, tumor formation, reproductive pathways, and neurological and autoimmune disorders. The effective functional role of miRNA can be reduced by chemical entities of antisense oligonucleotides and versatile small molecules that support the views of novel therapy of different human diseases. In this study, we have updated our current understanding for designing and synthesizing miRNA-controlling therapeutic chemicals. We have also proposed various

Indexed as

autoimmune disorderscardiovascular defectsmicroRNAsurveillancetumor formation

Identifiers

PMID27704139
PMCPMC5193465
OpenAlexW2560074356

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.