Evidence map›Paper›PMID 27704041›Full record

ArticleScience advances2016

Structure of myosin filaments from relaxed

Zhongjun Hu, Dianne W Taylor, Michael K Reedy, Robert J Edwards, Kenneth A Taylor

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 89 citations in OpenAlex.

  1. Article
  2. Ancestral and local adaptation contribute to dispersal out of the Qinghai-Tibet Plateau in a bumblebee.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Two Forms of Thick Filament in the Flight Muscle ofInternational journal of molecular sciences · 2024
    Article
  8. Structure of mavacamten-free human cardiac thick filaments within the sarcomere by cryoelectron tomography.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Structure of theInternational journal of molecular sciences · 2023
    Article
  14. John Squire and the myosin thick filament structure in muscle.Journal of muscle research and cell motility · 2023
    Review
  15. Nucleus Mechanosensing in Cardiomyocytes.International journal of molecular sciences · 2023
    Review
  16. Review
  17. Article
  18. Variants of the myosin interacting-heads motif.The Journal of general physiology · 2023
    Article
  19. Structure of the Flight Muscle Thick Filament from the Bumble Bee,International journal of molecular sciences · 2022
    Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zhongjun HuInstitute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306-4380, USA.
Dianne W TaylorInstitute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306-4380, USA.
Michael K ReedyDepartment of Cell Biology, Duke University Medical Center, Durham, NC 27607, USA.
Robert J EdwardsDepartment of Cell Biology, Duke University Medical Center, Durham, NC 27607, USA.ORCID 0000-0003-4446-1194
Kenneth A TaylorInstitute of Molecular Biophysics, Florida State University, Tallahassee, FL 32306-4380, USA.ORCID 0000-0001-9594-8360
Florida State University · USDuke University · US

Funding

EM STUDIES ON MUSCLER01GM030598 · NIGMS · FLORIDA STATE UNIVERSITY · PI TAYLOR, KENNETH ALLEN · 1985 to 2020
$4.9M
MYOFIBRILLAR STRUCTURE OF STRIATED MUSCLER01AR014317 · NIAMS · DUKE UNIVERSITY · PI EDWARDS, ROBERT JON · 1986 to 2016
$2.1M
Purchase of a FEI Titan Krios for 3-D EMS10RR025080 · NCRR · FLORIDA STATE UNIVERSITY · PI TAYLOR, KENNETH ALLEN · 2008 to 2008
$2.0M
Purchase of a direct electron camera for the Titan-Krios at FSUS10OD018142 · OD · FLORIDA STATE UNIVERSITY · PI TAYLOR, KENNETH ALLEN · 2014 to 2014
$384k
NCRR NIH HHS S10 RR025080NIAMS NIH HHS R01 AR014317NIGMS NIH HHS R01 GM030598NIH HHS S10 OD018142
6 · The paper itself

Abstract

We describe a cryo-electron microscopy three-dimensional image reconstruction of relaxed myosin II-containing thick filaments from the flight muscle of the giant water bug

Indexed as

Actin CytoskeletonAnimalsCryoelectron MicroscopyCytoskeletonFlight, AnimalHeteropteraImaging, Three-DimensionalModels, MolecularMuscle ContractionMusclesMyosinsMyosinselectron microscopyfibrillar muscleflightinIHRSRimage processingMuscle fibermyofilinparamyosinstretch activation

Identifiers

PMID27704041
PMCPMC5045269
OpenAlexW2524819112

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.