ReviewBioMed research international2016
Advanced Hemodynamic Management in Patients with Septic Shock.
Review in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- Automated hemodynamic resuscitation system for computer-controlled norepinephrine, vasopressin, and fluid therapy in endotoxin-induced shock: a feasibility and physiological proof-of-concept study.Intensive care medicine experimental · 2026Article
- Less-Invasive Hemodynamic and Tissue Perfusion Monitoring in Sepsis and Septic Shock: A Narrative Review.Journal of clinical medicine · 2026Review
- Sepsis, Management & Advances in Metabolomics.Nanotheranostics · 2024Review
- Pilot study: advanced haemodynamic monitoring after acute spinal cord injury-Keep the pressure up?BMC anesthesiology · 2022Article
- Acetaminophen-induced hypotension in sepsis.Journal of pharmaceutical health care and sciences · 2022Article
- State-of-the-art surgery for sigmoid diverticulitis.Langenbeck's archives of surgery · 2022Article
- CRRT influences PICCO measurements in febrile critically ill patients.Open medicine (Warsaw, Poland) · 2022Article
- An email-based survey of practice regarding hemodynamic monitoring and management in children with septic shock in China.Translational pediatrics · 2021Article
- Cardiac Output Evaluation on Septic Shock Patients: Comparison between Calibrated and Uncalibrated Devices during Vasopressor Therapy.Journal of clinical medicine · 2021Article
- Application of pulse index continuous cardiac output system in elderly patients with acute myocardial infarction complicated by cardiogenic shock: A prospective randomized study.World journal of clinical cases · 2019Article
- Central venous pressure value can assist in adjusting norepinephrine dosage after the initial resuscitation of septic shock.Chinese medical journal · 2019Article
- A comparison of ventricular systolic function indices provided by VolumeView/EV1000™ and left ventricular ejection fraction by echocardiography among septic shock patients.Journal of clinical monitoring and computing · 2019Observational
- Mortality outcomes based on ED qSOFA score and HIV status in a developing low income country.The American journal of emergency medicine · 2018Article
- Goal-directed therapy: hit early and personalize!Journal of clinical monitoring and computing · 2018Article
- [Changes in blood oxygen metabolism indices and their clinical significance in children with septic shock].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2017Article
- Sepsis in a Panorama: What the Cardiovascular Physician Should Know.Methodist DeBakey cardiovascular journalReview
- The use of bedside echocardiography for measuring cardiac index and systemic vascular resistance in pediatric patients with septic shock.Revista Brasileira de terapia intensivaObservational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In patients with sepsis and septic shock, the hemodynamic management in both early and later phases of these "organ dysfunction syndromes" is a key therapeutic component. It needs, however, to be differentiated between "early goal-directed therapy" (EGDT) as proposed for the first 6 hours of emergency department treatment by Rivers et al. in 2001 and "hemodynamic management" using advanced hemodynamic monitoring in the intensive care unit (ICU). Recent large trials demonstrated that nowadays protocolized EGDT does not seem to be superior to "usual care" in terms of a reduction in mortality in emergency department patients with early identified septic shock who promptly receive antibiotic therapy and fluid resuscitation. "Hemodynamic management" comprises (a) making the diagnosis of septic shock as one differential diagnosis of circulatory shock, (b) assessing the hemodynamic status including the identification of therapeutic conflicts, and (c) guiding therapeutic interventions. We propose two algorithms for hemodynamic management using transpulmonary thermodilution-derived variables aiming to optimize the cardiocirculatory and pulmonary status in adult ICU patients with septic shock. The complexity and heterogeneity of patients with septic shock implies that individualized approaches for hemodynamic management are mandatory. Defining individual hemodynamic target values for patients with septic shock in different phases of the disease must be the focus of future studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.