Evidence map›Paper›PMID 27703739›Full record

ArticleBJPsych open2015

Alterations in dorsal and ventral posterior cingulate connectivity in APOE

Rebecca Kerestes, Pramit M Phal, Chris Steward, Bradford A Moffat, Simon Salinas, Kay L Cox, Kathryn A Ellis, Elizabeth V Cyarto, David Ames, Ralph N Martins and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BJPsych open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Frontiers in aging neuroscience · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 2 countries.

Rebecca Kerestes, PhD, Department of Radiology, The Royal Melbourne Hospital, University of Melbourne, Parkville, Australia and Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Pramit M Phal, MBBS, FRANZCR.
Chris Steward, PhD.
Bradford A Moffat, PhD.
Simon Salinas, MSc (Eng), all at Department of Radiology, The Royal Melbourne Hospital, University of Melbourne, Parkville, Australia.
Kay L Cox, PhD, School of Medicine and Pharmacology, University of Western Australia, Perth, Australia.
Kathryn A Ellis, PhD, Academic Unit for Psychiatry of Old Age, St. Vincent's Health, Department of Psychiatry, University of Melbourne, Melbourne, Australia.
Elizabeth V Cyarto, PhD, National Ageing Research Institute, University of Melbourne, Parkville, Australia.
David Ames, MBBS, FRANZC, FRCPsych, Academic Unit for Psychiatry of Old Age, St Vincent's Health, Department of Psychiatry, University of Melbourne, Melbourne, Australia and National Ageing Research Institute, University of Melbourne, Parkville, Australia.
Ralph N Martins, PhD, School of Medical Sciences, Edith Cowan University, Perth, Australia.
Colin L Masters, MD, The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia.
Christopher C Rowe, MD, FRACP, Department of Nuclear Medicine and Centre for PET, Austin Health, Heidelberg, Australia.
Matthew J Sharman, PhD, School of Health Sciences, University of Tasmania, Hobart, Australia.
Olivier Salvado, PhD, Commonwealth Scientific Industrial Research Organization Preventative Health National Research Flagship, Australian e-Health Research Centre, Brisbane, Australia.
Cassandra Szoeke, MBBS, FRACP, PhD.
Michelle Lai, MBBS, MPH, Mmed, National Ageing Research Institute, University of Melbourne, Parkville, Australia.
Nicola T Lautenschlager, MD, Academic Unit for Psychiatry of Old Age, St. Vincent's Health, Department of Psychiatry, University of Melbourne, Melbourne, Australia and North Western Mental Health, Melbourne Health, Melbourne, Australia.
Patricia M Desmond, MD, Department of Radiology, The Royal Melbourne Hospital, University of Melbourne, Parkville, Australia.
University of Melbourne · AUThe Royal Melbourne Hospital · AUSt Vincent's Health · AUAustin Health · AUAustralian e-Health Research Centre · AUEdith Cowan University · AUFlorey Institute of Neuroscience and Mental Health · AUNational Ageing Research Institute · AUUniversity of Tasmania · AUUniversity of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent evidence suggests that exercise plays a role in cognition and that the posterior cingulate cortex (PCC) can be divided into dorsal and ventral subregions based on distinct connectivity patterns.

aimsTo examine the effect of physical activity and division of the PCC on brain functional connectivity measures in subjective memory complainers (SMC) carrying the epsilon 4 allele of apolipoprotein E (APOE

methodParticipants were 22 SMC carrying the APOE

results

conclusionsThe results provide the first evidence that DECLARATION OF INTEREST: D.A. has served on scientific advisory boards for Novartis, Eli Lilly, Janssen, Prana and Pfizer, and as Editor-in-Chief for COPYRIGHT AND USAGE: © The Royal College of Psychiatrists 2015. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) licence.

Identifiers

PMID27703739
PMCPMC4995563
OpenAlexW2180527885

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.