Evidence map›Paper›PMID 27703738›Full record

ArticleBJPsych open2015

An exploration of testosterone levels in patients with bipolar disorder.

Sarah C Wooderson, Peter Gallagher, Stuart Watson, Allan H Young

Open access · goldAbstract read
In one paragraph

Article in BJPsych open, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  4. Article
  5. Review
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  7. Review
  8. Comparison of salivary testosterone levels in different phases of bipolar I disorder and control group.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2018
    Article
  9. Observational
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sarah C Wooderson, MBPsS, BSc, MSc, PhD, Centre for Affective Disorders, Institute of Psychiatry, Psychology & Neuroscience (IoPPN), King's College London, UK.
Peter Gallagher, PhD, Institute of Neuroscience (Academic Psychiatry), Newcastle University, Newcastle, UK.
Stuart Watson, MBBS, MD, MRCPsych, Institute of Neuroscience, Newcastle University, Newcastle, UK.
Allan H Young, MBChB, MPhil, PhD, FRCPsych, FRCPC, Centre for Affective Disorders, IoPPN, King's College London, UK.
King's College London · GBNewcastle University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTestosterone influences well-being, mood and cognition and may play a role in the pathophysiology of bipolar disorder.

aimTo examine testosterone levels in patients with bipolar disorder compared with healthy controls.

methodWe examined baseline total testosterone levels and current depression scores in male and female patients with bipolar disorder and mild to moderate depression and healthy controls.

resultsA significant interaction between diagnosis and gender was observed (

conclusionsDisturbances in testosterone levels may represent an important neurobiological abnormality in bipolar disorder and may differ by gender. If these findings are confirmed, the use of gender appropriate treatment strategies for the normalisation of testosterone levels in bipolar disorder depression should be further explored. DECLARATION OF INTEREST: None. COPYRIGHT AND USAGE: © The Royal College of Psychiatrists 2015. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) licence.

Identifiers

PMID27703738
PMCPMC4995589
OpenAlexW2175966518

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.