Evidence map›Paper›PMID 27703664›Full record

ReviewF1000Research2016

Recent advances in T-cell engineering for use in immunotherapy.

Preeti Sharma, David M Kranz

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Cancer therapy with antibodies.Nature reviews. Cancer · 2024
    Review
  4. Article
  5. Bispecific antibodies targeting mutantScience immunology · 2021
    Article
  6. Article
  7. Structure-guided engineering of the affinity and specificity of CARs against Tn-glycopeptides.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  8. T Cell Reprogramming Against Cancer.Methods in molecular biology (Clifton, N.J.) · 2020
    Review
  9. Article
  10. Review
  11. Identifying neoantigens for use in immunotherapy.Mammalian genome : official journal of the International Mammalian Genome Society · 2018
    Review
  12. Article
  13. IL-2 and Beyond in Cancer Immunotherapy.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2018
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Preeti SharmaDepartment of Biochemistry, University of Illinois, Urbana, IL, USA.
David M KranzDepartment of Biochemistry, University of Illinois, Urbana, IL, USA.
University of Illinois Urbana-Champaign · US

Funding

Engineering T Cell Receptors for Adoptive Cell TherapiesR01CA178844 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI KRANZ, DAVID M. · 2014 to 2018
$1.6M
Influence of structurally related self-peptides on T cell-mediated therapiesR21CA187592 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI KRANZ, DAVID M. · 2015 to 2016
$337k
NCI NIH HHS R01 CA178844NCI NIH HHS R21 CA187592
6 · The paper itself

Abstract

Adoptive T-cell therapies have shown exceptional promise in the treatment of cancer, especially B-cell malignancies. Two distinct strategies have been used to redirect the activity of

Indexed as

chimeric antigen receptorimmunotherapyneoantigensreceptorT cell

Identifiers

PMID27703664
PMCPMC5031132
OpenAlexW2521465606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.