Evidence map›Paper›PMID 27703361›Full record

ArticleNeuropsychiatric disease and treatment2016

Mean platelet volume and red cell distribution width levels in initial evaluation of panic disorder.

Mehmet Asoglu, Mehmet Aslan, Okan Imre, Yuksel Kivrak, Oznur Akil, Emin Savik, Hasan Buyukaslan, Ulker Fedai, Abdurrahman Altındag

Open access · goldAbstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Depression and Anxiety Symptoms Are Associated with Mean Platelet Volume in Autoimmune Disorders.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mehmet AsogluDepartment of Psychiatry, Faculty of Medicine, Harran University, Sanliurfa.
Mehmet AslanDepartment of Internal Medicine, Faculty of Medicine, Yuzuncu Yil University, Van.
Okan ImreDepartment of Psychiatry, Faculty of Medicine, Harran University, Sanliurfa.
Yuksel KivrakDepartment of Psychiatry, Faculty of Medicine, Kafkas University, Kars.
Oznur AkilDepartment of Psychiatry, Faculty of Medicine, Harran University, Sanliurfa.
Emin SavikDepartment of Clinical Biochemistry, Faculty of Medicine, Harran University.
Hasan BuyukaslanDepartment of Emergency Medicine, Faculty of Medicine, Harran University, Sanliurfa.
Ulker FedaiDepartment of Psychiatry, Faculty of Medicine, Harran University, Sanliurfa.
Abdurrahman AltındagDepartment of Psychiatry, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey.
Harran University · TRGaziantep University · TRKafkas University · TRVan Yüzüncü Yıl Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs the relationship between psychological stress and platelet activation has been widely studied in recent years, activated platelets lead to certain biochemical changes, which occur in the brain in patients with mental disorders. However, data relating to the mean platelet volume (MPV) in patients with panic disorder (PD) are both limited and controversial. Herein, we aimed to evaluate, for the first time, the red cell distribution width (RDW) levels combined with MPV levels in patients with PD. PATIENTS AND

methodsBetween January 2012 and June 2015, data of 30 treatment-naïve patients (16 females, 14 males; mean age: 37±10 years; range: 18-59 years) who were diagnosed with PD and 25 age- and sex-matched healthy volunteers (10 females, 15 males; mean age: 36±13 years; range: 18-59 years) (control group) were retrospectively analyzed. The white blood cell count (WBC), MPV, and RDW levels were measured in both groups.

resultsThe mean WBC, MPV, and RDW levels were 9,173.03±2,400.31/mm

conclusionOur study results are the first to demonstrate that the RDW levels combined with MPV levels significantly increase among patients with PD. We believe that increased RDW and MPV levels can be used as a novel marker for PD.

Indexed as

mean platelet volumepanic disorderplatelet numberred cell distribution widthwhite blood cell count

Identifiers

PMID27703361
PMCPMC5036575
OpenAlexW2521198873

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.