ArticleInternational journal of nanomedicine
Treatment of natural mammary gland tumors in canines and felines using gold nanorods-assisted plasmonic photothermal therapy to induce tumor apoptosis.
Article in International journal of nanomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 79 citations in OpenAlex.
- Research progress on new physical therapies for cancer (Review).Oncology letters · 2025Review
- Plasmonic Magnesium Nanoparticles Are Efficient Nanoheaters.Nano letters · 2023Article
- Nanoparticle-Mediated Photothermal Therapy Limitation in Clinical Applications Regarding Pain Management.Nanomaterials (Basel, Switzerland) · 2022Review
- Optimization of endothelial growth factor receptor monoclonal antibody-gold nanorods photothermal therapy for laryngeal squamous cell carcinoma.Bioengineered · 2022Article
- Mild hyperthermia induced by gold nanorods acts as a dual-edge blade in the fate of SH-SY5Y cells via autophagy.Scientific reports · 2021Article
- Assessment and Modeling of Plasmonic Photothermal Therapy Delivered via a Fiberoptic Microneedle Device Ex Vivo.Pharmaceutics · 2021Article
- A Systematic Review of Complementary and Alternative Veterinary Medicine: "Miscellaneous Therapies".Animals : an open access journal from MDPI · 2021Review
- Effects of macrophage polarization on gold nanoparticle-assisted plasmonic photothermal therapy.RSC advances · 2021Article
- The past, present, and future of breast cancer models for nanomedicine development.Advanced drug delivery reviews · 2021Review
- Applications and challenges of thermoplasmonics.Nature materials · 2020Review
- Green Plasmonic Nanoparticles and Bio-Inspired Stimuli-Responsive Vesicles in Cancer Therapy Application.Nanomaterials (Basel, Switzerland) · 2020Review
- Magnetic-plasmonic Ni@Au core-shell nanoparticle arrays and their SERS properties.RSC advances · 2020Article
- Nanomaterial-Based Tumor Photothermal Immunotherapy.International journal of nanomedicine · 2020Review
- Biotherapeutic Antibodies for the Treatment of Head and Neck Cancer: Current Approaches and Future Considerations of Photothermal Therapies.Frontiers in oncology · 2020Review
- Nanotechnology advances towards development of targeted-treatment for obesity.Journal of nanobiotechnology · 2019Review
- Gold Nanorod-Assisted Photothermal Therapy Decreases Bleeding during Breast Cancer Surgery in Dogs and Cats.Cancers · 2019Article
- Fractionated photothermal therapy in a murine tumor model: comparison with single dose.International journal of nanomedicine · 2019Article
- Laser-driven structural transformations in dextran-RSC advances · 2018Article
- Gold Nanorod Photothermal Therapy Alters Cell Junctions and Actin Network in Inhibiting Cancer Cell Collective Migration.ACS nano · 2018Article
- Biocompatible tumor-targeting nanocomposites based on CuS for tumor imaging and photothermal therapy.RSC advances · 2018Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plasmonic photothermal therapy (PPTT) is a cancer therapy in which gold nanorods are injected at the site of a tumor before near-infrared light is transiently applied to the tumor causing localized cell death. Previously, PPTT studies have been carried out on xenograft mice models. Herein, we report a study showing the feasibility of PPTT as applied to natural tumors in the mammary glands of dogs and cats, which more realistically represent their human equivalents at the molecular level. We optimized a regime of three low PPTT doses at 2-week intervals that ablated tumors mainly via apoptosis in 13 natural mammary gland tumors from seven animals. Histopathology, X-ray, blood profiles, and comprehensive examinations were used for both the diagnosis and the evaluation of tumor statuses before and after treatment. Histopathology results showed an obvious reduction in the cancer grade shortly after the first treatment and a complete regression after the third treatment. Blood tests showed no obvious change in liver and kidney functions. Similarly, X-ray diffraction showed no metastasis after 1 year of treatment. In conclusion, our study suggests the feasibility of applying the gold nanorods-PPTT on natural tumors in dogs and cats without any relapse or toxicity effects after 1 year of treatment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.