Evidence map›Paper›PMID 27703349›Full record

ReviewInternational journal of nanomedicine

TiO

Qun Wang, Jian-Ying Huang, Hua-Qiong Li, Zhong Chen, Allan Zi-Jian Zhao, Yi Wang, Ke-Qin Zhang, Hong-Tao Sun, Salem S Al-Deyab, Yue-Kun Lai

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 141 citations in OpenAlex.

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  19. TiOJournal of functional biomaterials · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Qun WangNational Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou; College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, People's Republic of China.
Jian-Ying HuangNational Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou.
Hua-Qiong LiWenzhou Institute of Biomaterials and Engineering, Chinese Academy of Sciences, Wenzhou, People's Republic of China.
Zhong ChenSchool of Materials Science and Engineering, Nanyang Technological University, Singapore, Singapore.
Allan Zi-Jian ZhaoWenzhou Institute of Biomaterials and Engineering, Chinese Academy of Sciences, Wenzhou, People's Republic of China.
Yi WangWenzhou Institute of Biomaterials and Engineering, Chinese Academy of Sciences, Wenzhou, People's Republic of China.
Ke-Qin ZhangNational Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou.
Hong-Tao SunCollege of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, People's Republic of China.
Salem S Al-DeyabDepartment of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
Yue-Kun LaiNational Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou.
Soochow University · CNChinese Academy of Sciences · CNKing Saud University · SANanyang Technological University · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Titania nanotube (TNT) arrays are recognized as promising materials for localized drug delivery implants because of their excellent properties and facile preparation process. This review highlights the concept of localized drug delivery systems based on TNTs, considering their outstanding biocompatibility in a series of ex vivo and in vivo studies. Considering the safety of TNT implants in the host body, studies of the biocompatibility present significant importance for the clinical application of TNT implants. Toward smart TNT platforms for sustainable drug delivery, several advanced approaches were presented in this review, including controlled release triggered by temperature, light, radiofrequency magnetism, and ultrasonic stimulation. Moreover, TNT implants used in medical therapy have been demonstrated by various examples including dentistry, orthopedic implants, cardiovascular stents, and so on. Finally, a future perspective of TNTs for clinical applications is provided.

Indexed as

NanotubesAnimalsDrug Delivery SystemsHumansHydrogen-Ion ConcentrationLightMagnetic FieldsMaterials TestingProstheses and ImplantsTemperatureTitaniumTitaniumtitanium dioxideanodizationdrug deliveryorthopedic implantTiO2 nanotubes

Identifiers

PMID27703349
PMCPMC5036548
OpenAlexW2522287896

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.