Evidence map›Paper›PMID 27703035›Full record

ArticleThe Journal of infectious diseases2016

CD4+ T Cells Coexpressing CD134 (OX40) Harbor Significantly Increased Levels of Human Herpesvirus 6B DNA Following Umbilical Cord Blood Transplantation.

Joshua C Pritchett, Jaime S Green, Angela M Thomm, Konstance K Knox, Michael R Verneris, Troy C Lund

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Joshua C PritchettDivision of Blood and Marrow Transplantation, Department of Pediatrics.
Jaime S GreenDivision of Infectious Disease, Department of Medicine, University of Minnesota Medical School, Minneapolis.
Angela M ThommCoppe Healthcare Solutions, Waukesha, Wisconsin.
Konstance K KnoxCoppe Healthcare Solutions, Waukesha, Wisconsin.
Michael R VernerisDivision of Blood and Marrow Transplantation, Department of Pediatrics.
Troy C LundDivision of Blood and Marrow Transplantation, Department of Pediatrics.
University of Minnesota Medical Center · US

Funding

Trial Design and Biostatistical Support CoreP01CA065493 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Mark J Osborn · 1995 to 2026
$48.2M
Lymphoid Tissue Inducer/NK22 Cells and Post-transplant Immune RecoveryR01AI100879 · NIAID · UNIVERSITY OF MINNESOTA · PI VERNERIS, MICHAEL R. · 2013 to 2017
$1.9M
NCI NIH HHS P01 CA065493NIAID NIH HHS R01 AI100879
6 · The paper itself

Abstract

Human herpesvirus 6B (HHV-6B) commonly reactivates after umbilical cord blood transplantation (UCBT) and is associated with delayed engraftment, fever, rash, and central nervous system dysfunction. Recently, CD134 (OX40) has been implicated as a potential viral entry receptor. We evaluated CD4

Indexed as

AdultCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesChildCohort StudiesDNA, ViralFemaleFetal BloodHerpesvirus 6, HumanHumansInfantMaleMiddle AgedReceptors, OX40Roseolovirus InfectionsTransplantationDNA, ViralReceptors, OX40TNFRSF4 protein, humanCD134herpesvirusHHV-6OX40umbilical cord blood transplantation

Identifiers

PMID27703035
PMCPMC5142091
OpenAlexW2528653240

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.