Evidence map›Paper›PMID 27702821›Full record

Trial reportClinical cancer research : an official journal of the American Association for Cancer Research2017

Integrative Development of a TLR8 Agonist for Ovarian Cancer Chemoimmunotherapy.

Bradley J Monk, Andrea Facciabene, William E Brady, Carol A Aghajanian, Paula M Fracasso, Joan L Walker, Heather A Lankes, Kristi L Manjarrez, Gwenn-Äel H Danet-Desnoyers, Katherine M Bell-McGuinn and 4 more

Open access · bronzeAbstract readClinical Trial, Phase IRandomized Controlled Trial
In one paragraph

Trial report in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Bradley J MonkArizona Oncology (US Oncology Network), University of Arizona College of Medicine-Phoenix, Creighton University School of Medicine at St. Joseph's Hospital, Phoenix, Arizona. Bradley.monk@usoncology.com.
Andrea FacciabeneUniversity of Pennsylvania, Philadelphia, Pennsylvania.
William E BradyNRG Oncology Statistics and Data Management Center, Roswell Park Cancer Institute, Buffalo, New York.
Carol A AghajanianMemorial Sloan Kettering Cancer Center, New York, New York.
Paula M FracassoUniversity of Virginia, Charlottesville, Virginia.
Joan L WalkerUniversity of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
Heather A LankesNRG Oncology Statistics and Data Management Center, Roswell Park Cancer Institute, Buffalo, New York.
Kristi L ManjarrezVentiRx Pharmaceuticals, Seattle, Washington.
Gwenn-Äel H Danet-DesnoyersUniversity of Pennsylvania, Philadelphia, Pennsylvania.
Katherine M Bell-McGuinnMemorial Sloan Kettering Cancer Center, New York, New York.
Carolyn K McCourtWashington University School of Medicine, St. Louis, Missouri.
Alexander MalykhinUniversity of Pennsylvania, Philadelphia, Pennsylvania.
Robert M HershbergVentiRx Pharmaceuticals, Seattle, Washington.
George CoukosUniversity of Pennsylvania, Philadelphia, Pennsylvania.
University of Pennsylvania · USMemorial Sloan Kettering Cancer Center · US

Funding

NRG Oncology Network Group Operations Center - GY9 BIQSFP Reports/BudgetsU10CA180868 · NCI · NRG ONCOLOGY FOUNDATION, INC. · PI NORMAN WOLMARK · 2014 to 2026
$206.8M
Statistics CoreU10CA180822 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI James J. Dignam · 2014 to 2026
$146.4M
NRG Oncology NCORP Research Base-BIQSFPUG1CA189867 · NCI · NRG ONCOLOGY FOUNDATION, INC. · PI Deborah Watkins Bruner, Lisa A. Kachnic · 2014 to 2026
$140.5M
GYNECOLOGIC ONCOLOGY GROUP HEADQUARTERSU10CA027469 · NCI · GYNECOLOGIC ONCOLOGY GROUP · PI DISAIA, PHILIP J. · 1985 to 2013
$132.6M
GYNECOLOGIC ONCOLOGY GROUP STATISTICAL OFFICEU10CA037517 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI BLESSING, JOHN A · 1985 to 2013
$67.4M
NRG Oncology Biospecimen BankU24CA196067 · NCI · NRG ONCOLOGY FOUNDATION, INC. · PI Tanner J. Freeman, Nilsa Del Carmen Ramirez Milan · 2015 to 2026
$42.6M
Washington University/ Siteman Cancer Center Lead Academic SiteU10CA180833 · NCI · WASHINGTON UNIVERSITY · PI BARTLETT, NANCY L, KOZOWER, BENJAMIN D · 2014 to 2018
$7.6M
Gynecologic Oncology Group Specimen BankingU24CA114793 · NCI · GYNECOLOGIC ONCOLOGY GROUP · PI DISAIA, PHILIP J. · 2005 to 2014
$7.0M
NCI NIH HHS U10 CA027469NCI NIH HHS U10 CA037517NCI NIH HHS U10 CA180822NCI NIH HHS U10 CA180833NCI NIH HHS U10 CA180868NCI NIH HHS U24 CA114793NCI NIH HHS U24 CA196067NCI NIH HHS UG1 CA189867
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAnimalsAntineoplastic Combined Chemotherapy ProtocolsBenzazepinesBlotting, WesternDoxorubicinFemaleHumansImmunotherapyMacaca fascicularisMaleMaximum Tolerated DoseMiceMice, Inbred NODMice, SCIDMiddle AgedBenzazepinesDoxorubicinliposomal doxorubicinPolyethylene GlycolsTLR8 protein, humanToll-Like Receptor 8VTX-2337

Identifiers

PMID27702821
PMCPMC5437973
OpenAlexW2527845016

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.