Evidence map›Paper›PMID 27702820›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017

Fibroblast Subtypes Regulate Responsiveness of Luminal Breast Cancer to Estrogen.

Heather M Brechbuhl, Jessica Finlay-Schultz, Tomomi M Yamamoto, Austin E Gillen, Diana M Cittelly, Aik-Choon Tan, Sharon B Sams, Manoj M Pillai, Anthony D Elias, William A Robinson and 2 more

Open access · greenAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 153 papers.

0numbers the graph read from it
0cells of the map it votes in
153citing papers in PubMed
6.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

153 citing papers in PubMed, 229 citations in OpenAlex.

  1. Review
  2. GPX8Oncogene · 2026
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  14. The fibroinflammatory response in cancer.Nature reviews. Cancer · 2025
    Review
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93 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Heather M BrechbuhlDepartment of Medicine, Division of Medical Oncology, University of Colorado Denver, Aurora, Colorado. Peter.Kabos@ucdenver.edu heather.brechbuhl@ucdenver.edu.
Jessica Finlay-SchultzDepartment of Pathology, University of Colorado Denver, Aurora, Colorado.
Tomomi M YamamotoDepartment of Medicine, Division of Medical Oncology, University of Colorado Denver, Aurora, Colorado.
Austin E GillenDepartment of Medicine, Division of Medical Oncology, University of Colorado Denver, Aurora, Colorado.
Diana M CittellyDepartment of Pathology, University of Colorado Denver, Aurora, Colorado.
Aik-Choon TanDepartment of Medicine, Division of Medical Oncology, University of Colorado Denver, Aurora, Colorado.
Sharon B SamsDepartment of Pathology, University of Colorado Denver, Aurora, Colorado.
Manoj M PillaiSection of Hematology, Division of Hematology, Yale Cancer Center and Yale University School of Medicine, New Haven, Connecticut.
Anthony D EliasDepartment of Medicine, Division of Medical Oncology, University of Colorado Denver, Aurora, Colorado.
William A RobinsonDepartment of Medicine, Division of Medical Oncology, University of Colorado Denver, Aurora, Colorado.
Carol A SartoriusDepartment of Pathology, University of Colorado Denver, Aurora, Colorado.
Peter KabosDepartment of Medicine, Division of Medical Oncology, University of Colorado Denver, Aurora, Colorado. Peter.Kabos@ucdenver.edu heather.brechbuhl@ucdenver.edu.
University of Colorado Denver · USYale Cancer Center · US

Funding

University of Colorado Cancer Center Support Grant - Lung Cancer Patient-Derived Xenografts with Autologous Human Immune SystemsP30CA046934 · NCI · UNIVERSITY OF COLORADO DENVER · PI James V Degregori · 1988 to 2026
$117.0M
Yale Pathology Tissue Services Shared ResourceP30CA016359 · NCI · YALE UNIVERSITY · PI DAVID L RIMM · 1985 to 2026
$85.0M
Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Wendy M Kohrt · 1995 to 2026
$32.6M
Hormones and Tumor Initiating Cells in Human Breast CancersR01CA140985 · NCI · UNIVERSITY OF COLORADO DENVER · PI SARTORIUS, CAROL ANN · 2011 to 2020
$3.0M
Role of microRNAs in regulation of the marrow microenvironmentR01HL104070 · NHLBI · YALE UNIVERSITY · PI PILLAI, MANOJ M. · 2011 to 2015
$2.2M
Cancer-associated fibroblasts in estrogen receptor positive breast cancer.R01CA205044 · NCI · UNIVERSITY OF COLORADO DENVER · PI KABOS, PETER · 2016 to 2020
$1.8M
Regulation of anti-endocrine resistance of breast cancer by a network of non-codiK08CA164048 · NCI · UNIVERSITY OF COLORADO DENVER · PI KABOS, PETER · 2012 to 2016
$859k
NCATS NIH HHS UL1 TR001082NCI NIH HHS K08 CA164048NCI NIH HHS P30 CA016359NCI NIH HHS P30 CA046934NCI NIH HHS R01 CA140985NCI NIH HHS R01 CA205044NHLBI NIH HHS R01 HL104070
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic Agents, HormonalBreast NeoplasmsCancer-Associated FibroblastsCD146 AntigenDrug Resistance, NeoplasmEstrogensFemaleGene Expression Regulation, NeoplasticHumansMCF-7 CellsReceptors, EstrogenTamoxifenTumor MicroenvironmentAntineoplastic Agents, HormonalCD146 AntigenEstrogensMCAM protein, humanReceptors, EstrogenTamoxifen

Identifiers

PMID27702820
PMCPMC5378660
OpenAlexW2529550497

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.