ArticleAmerican journal of epidemiology2016
Estimation of Inorganic Arsenic Exposure in Populations With Frequent Seafood Intake: Evidence From MESA and NHANES.
Article in American journal of epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 3 of them syntheses that pooled it.
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Who cites it
57 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Contribution of arsenic and uranium in private wells and community water systems to urinary biomarkers in US adults: The Strong Heart Study and the Multi-Ethnic Study of Atherosclerosis.Journal of exposure science & environmental epidemiology · 2024Pooled it
- Urinary arsenic and heart disease mortality in NHANES 2003-2014.Environmental research · 2021Pooled it
- Toenails as a biomarker of exposure to arsenic: A review.Environmental research · 2021Pooled it
- Identifying dietary sources and patterns of exposure to toxic metals and other trace elements in Swedish toddlers and young children.Journal of exposure science & environmental epidemiology · 2026Article
- Evaluation of integrated, multimedia biomarkers of prenatal metals exposure in association with child neurodevelopment in Puerto Rico.Journal of exposure science & environmental epidemiology · 2026Article
- Heavy Metal Toxicity in Clinical and Environmental Health: Sources, Mechanisms, Diagnostics, and Evidence-Based Management of Mercury, Lead, Cadmium, and Arsenic.International journal of molecular sciences · 2026Review
- Drinking water arsenic, urinary arsenic biomarkers, and cognitive impairment in the REGARDS study.Environmental research · 2026Article
- Arsenic species and lipid metabolism under low-to-moderate arsenic exposure: evidence from NHANES and a Chinese adult population.Frontiers in endocrinology · 2026Article
- Associations Between Urinary Metal Levels and Incident Heart Failure: A Multi-Cohort Analysis.JACC. Heart failure · 2025Article
- Geographic and Sociodemographic Differences in Cadmium Exposure in the Multi-Ethnic Study of Atherosclerosis (MESA).Exposure and health · 2025Article
- Review
- Association of urinary arsenic concentrations with inflammation: overall and by folate intake, body mass index, and gender.International journal of hygiene and environmental health · 2025Article
- Uranium exposure and kidney tubule biomarkers in the Multi-Ethnic Study of Atherosclerosis (MESA).Environmental research · 2025Article
- Arsenic speciation analysis in human urine for long term epidemiological studies: The Multi-Ethnic Study of Atherosclerosis (MESA).Environmental research · 2024Article
- Association of Urinary Metals With Cardiovascular Disease Incidence and All-Cause Mortality in the Multi-Ethnic Study of Atherosclerosis (MESA).Circulation · 2024Article
- Urinary arsenic species and birth outcomes in Tacna, Peru, 2019: a prospective cohort study.UCL open. Environment · 2024Article
- Prenatal exposure to metal mixtures and lung function in children from the New Hampshire birth cohort study.Environmental research · 2023Article
- Biomonitoring of inorganic arsenic species in pregnancy.Journal of exposure science & environmental epidemiology · 2023Review
- Effects of Dietary Intake of Arsenosugars and Other Organic Arsenic Species on Studies of Arsenic Methylation Efficiency in Humans.Environment & health (Washington, D.C.) · 2023Review
- Impact of lowering the US maximum contaminant level on arsenic exposure: Differences by race, region, and water arsenic in NHANES 2003-2014.Environmental pollution (Barking, Essex : 1987) · 2023Article
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Authors and funding
10 authors.
Funding
Abstract
The sum of urinary inorganic arsenic (iAs) and methylated arsenic (monomethylarsonate and dimethylarsinate (DMA)) species is the main biomarker of iAs exposure. Assessing iAs exposure, however, is difficult in populations with moderate-to-high seafood intakes. In the present study, we used subsamples from the Multi-Ethnic Study of Atherosclerosis (2000-2002) (n = 310) and the 2003-2006 National Health and Nutrition Examination Survey (n = 1,175). We calibrated urinary concentrations of non-seafood-derived iAs, DMA, and methylarsonate, as well as the sum of inorganic and methylated arsenic species, in the Multi-Ethnic Study of Atherosclerosis and of DMA in the National Health and Nutrition Examination Survey by regressing their original concentrations by arsenobetaine and extracting model residuals. To confirm that calibrated biomarkers reflected iAs exposure but not seafood intake, we compared urinary arsenic concentrations by levels of seafood and rice intakes. Self-reported seafood intakes, estimated n-3 polyunsaturated fatty acid levels, and measured n-3 polyunsaturated fatty acid levels were positively associated with the original urinary arsenic biomarkers. Using the calibrated arsenic biomarkers, we found a marked attenuation of the associations with self-reported seafood intake and estimated or measured n-3 fatty acids, whereas associations with self-reported rice intake remained similar. Our residual-based method provides estimates of iAs exposure and metabolism for each participant that no longer reflect seafood intake and can facilitate research about low-to-moderate levels of iAs exposure in populations with high seafood intakes.
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