Evidence map›Paper›PMID 27702645›Full record

ArticleNeuroscience2016

Timing of amphetamine exposure in relation to puberty onset determines its effects on anhedonia, exploratory behavior, and dopamine D

Shuo Kang, Mariah M Wu, Roberto Galvez, Joshua M Gulley

Abstract read
In one paragraph

Article in Neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Peri-adolescent exposure to (meth)amphetamine in animal models.International review of neurobiology · 2022
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Combined ∆Psychopharmacology · 2019
    Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shuo KangNeuroscience Program, University of Illinois at Urbana-Champaign, IL, USA; Beckman Institute for Advanced Science, University of Illinois at Urbana-Champaign, IL, USA.
Mariah M WuDepartment of Psychology, University of Illinois at Urbana-Champaign, IL, USA.
Roberto GalvezDepartment of Psychology, University of Illinois at Urbana-Champaign, IL, USA; Neuroscience Program, University of Illinois at Urbana-Champaign, IL, USA; Beckman Institute for Advanced Science, University of Illinois at Urbana-Champaign, IL, USA.
Joshua M GulleyDepartment of Psychology, University of Illinois at Urbana-Champaign, IL, USA; Neuroscience Program, University of Illinois at Urbana-Champaign, IL, USA; Beckman Institute for Advanced Science, University of Illinois at Urbana-Champaign, IL, USA. Electronic address: jgulley@illinois.edu.
University of Illinois Urbana-Champaign · US

Funding

Mechanisms of amphetamine-induced plasticity in adolescents compared to adultsR01DA029815 · NIDA · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI GULLEY, JOSHUA M · 2011 to 2015
$1.5M
NIDA NIH HHS R01 DA029815
6 · The paper itself

Abstract

Non-medical use of amphetamine (AMPH) among adolescents is prevalent, which is problematic given the potential consequences of developmental drug exposure on brain function and behavior. Previously we found in adult male rats that AMPH exposure starting before puberty induces a persistent decrease in dopamine D

Indexed as

AmphetamineAmphetamine-Related DisordersAnhedoniaAnimalsCentral Nervous System StimulantsDietary SucroseExploratory BehaviorFemaleMaleModels, AnimalNucleus AccumbensPrefrontal CortexRats, Sprague-DawleyReceptors, Dopamine D1Sexual MaturationSubstance Withdrawal SyndromeAmphetamineCentral Nervous System StimulantsDietary SucroseReceptors, Dopamine D1adolescenceD(1) receptorelevated plus mazeprefrontal cortexpubertyrisk taking

Identifiers

PMID27702645
PMCPMC5118128
OpenAlexW2527820524

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.